Acute Toxin-mediated Rhabdomyolysis During Treatment With Trimethoprim-sulfamethoxazole.
Journal
Clinical practice and cases in emergency medicine
ISSN: 2474-252X
Titre abrégé: Clin Pract Cases Emerg Med
Pays: United States
ID NLM: 101718968
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
06
02
2019
revised:
06
07
2019
accepted:
23
07
2019
entrez:
26
11
2019
pubmed:
26
11
2019
medline:
26
11
2019
Statut:
epublish
Résumé
Rhabdomyolysis is a condition in which skeletal muscle breakdown causes the release of intracellular components into the bloodstream - defined as elevations in serum creatine kinase levels. The etiology of rhabdomyolysis is varied and may be the result of toxin-mediated mechanisms or metabolic derangements, or they may develop secondary to other conditions such as seizures, trauma and prolonged immobilization. In this case, we present a patient with suspected acute toxin-mediated rhabdomyolysis in the setting of trimethoprim-sulfamethoxazole (TMP-SMX) therapy for urinary tract infection. To our knowledge, this marks the fifth case report of an otherwise healthy patient diagnosed with rhabdomyolysis thought to be secondary to TMP-SMX.
Identifiants
pubmed: 31763587
doi: 10.5811/cpcem.2019.7.42688
pii: cpcem-03-357
pmc: PMC6861050
doi:
Types de publication
Case Reports
Langues
eng
Pagination
357-360Informations de copyright
Copyright: © 2019 Sperandeo et al.
Déclaration de conflit d'intérêts
Conflicts of Interest: By the CPC-EM article submission agreement, all authors are required to disclose all affiliations, funding sources and financial or management relationships that could be perceived as potential sources of bias. The authors disclosed none.
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