Quantification of Head Shape from Three-Dimensional Photography for Presurgical and Postsurgical Evaluation of Craniosynostosis.


Journal

Plastic and reconstructive surgery
ISSN: 1529-4242
Titre abrégé: Plast Reconstr Surg
Pays: United States
ID NLM: 1306050

Informations de publication

Date de publication:
12 2019
Historique:
entrez: 26 11 2019
pubmed: 26 11 2019
medline: 3 3 2020
Statut: ppublish

Résumé

Evaluation of surgical treatment for craniosynostosis is typically based on subjective visual assessment or simple clinical metrics of cranial shape that are prone to interobserver variability. Three-dimensional photography provides cheap and noninvasive information to assess surgical outcomes, but there are no clinical tools to analyze it. The authors aim to objectively and automatically quantify head shape from three-dimensional photography. The authors present an automatic method to quantify intuitive metrics of local head shape from three-dimensional photography using a normative statistical head shape model built from 201 subjects. The authors use these metrics together with a machine learning classifier to distinguish between patients with (n = 266) and without (n = 201) craniosynostosis (aged 0 to 6 years). The authors also use their algorithms to quantify objectively local surgical head shape improvements on 18 patients with presurgical and postsurgical three-dimensional photographs. The authors' methods detected craniosynostosis automatically with 94.74 percent sensitivity and 96.02 percent specificity. Within the data set of patients with craniosynostosis, the authors identified correctly the fused sutures with 99.51 percent sensitivity and 99.13 percent specificity. When the authors compared quantitatively the presurgical and postsurgical head shapes of patients with craniosynostosis, they obtained a significant reduction of head shape abnormalities (p < 0.05), in agreement with the treatment approach and the clinical observations. Quantitative head shape analysis and three-dimensional photography provide an accurate and objective tool to screen for head shape abnormalities at low cost and avoiding imaging with radiation and/or sedation. The authors' automatic quantitative framework allows for the evaluation of surgical outcomes and has the potential to detect relapses. Diagnostic, I.

Sections du résumé

BACKGROUND
Evaluation of surgical treatment for craniosynostosis is typically based on subjective visual assessment or simple clinical metrics of cranial shape that are prone to interobserver variability. Three-dimensional photography provides cheap and noninvasive information to assess surgical outcomes, but there are no clinical tools to analyze it. The authors aim to objectively and automatically quantify head shape from three-dimensional photography.
METHODS
The authors present an automatic method to quantify intuitive metrics of local head shape from three-dimensional photography using a normative statistical head shape model built from 201 subjects. The authors use these metrics together with a machine learning classifier to distinguish between patients with (n = 266) and without (n = 201) craniosynostosis (aged 0 to 6 years). The authors also use their algorithms to quantify objectively local surgical head shape improvements on 18 patients with presurgical and postsurgical three-dimensional photographs.
RESULTS
The authors' methods detected craniosynostosis automatically with 94.74 percent sensitivity and 96.02 percent specificity. Within the data set of patients with craniosynostosis, the authors identified correctly the fused sutures with 99.51 percent sensitivity and 99.13 percent specificity. When the authors compared quantitatively the presurgical and postsurgical head shapes of patients with craniosynostosis, they obtained a significant reduction of head shape abnormalities (p < 0.05), in agreement with the treatment approach and the clinical observations.
CONCLUSIONS
Quantitative head shape analysis and three-dimensional photography provide an accurate and objective tool to screen for head shape abnormalities at low cost and avoiding imaging with radiation and/or sedation. The authors' automatic quantitative framework allows for the evaluation of surgical outcomes and has the potential to detect relapses.
CLINICAL QUESTION/LEVEL OF EVIDENCE
Diagnostic, I.

Identifiants

pubmed: 31764657
doi: 10.1097/PRS.0000000000006260
pii: 00006534-201912000-00032
pmc: PMC6905129
mid: NIHMS1535189
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1051e-1060e

Subventions

Organisme : NICHD NIH HHS
ID : R42 HD081712
Pays : United States

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Auteurs

Antonio R Porras (AR)

From the Sheikh Zayed Institute for Pediatric Surgical Innovation and the Departments of Neurosurgery and Plastic and Reconstructive Surgery, Children's National Health System; Kitware, Inc.; and the Departments of Radiology, Pediatrics, and Biomedical Engineering, George Washington University.

Liyun Tu (L)

From the Sheikh Zayed Institute for Pediatric Surgical Innovation and the Departments of Neurosurgery and Plastic and Reconstructive Surgery, Children's National Health System; Kitware, Inc.; and the Departments of Radiology, Pediatrics, and Biomedical Engineering, George Washington University.

Deki Tsering (D)

From the Sheikh Zayed Institute for Pediatric Surgical Innovation and the Departments of Neurosurgery and Plastic and Reconstructive Surgery, Children's National Health System; Kitware, Inc.; and the Departments of Radiology, Pediatrics, and Biomedical Engineering, George Washington University.

Esperanza Mantilla (E)

From the Sheikh Zayed Institute for Pediatric Surgical Innovation and the Departments of Neurosurgery and Plastic and Reconstructive Surgery, Children's National Health System; Kitware, Inc.; and the Departments of Radiology, Pediatrics, and Biomedical Engineering, George Washington University.

Albert Oh (A)

From the Sheikh Zayed Institute for Pediatric Surgical Innovation and the Departments of Neurosurgery and Plastic and Reconstructive Surgery, Children's National Health System; Kitware, Inc.; and the Departments of Radiology, Pediatrics, and Biomedical Engineering, George Washington University.

Andinet Enquobahrie (A)

From the Sheikh Zayed Institute for Pediatric Surgical Innovation and the Departments of Neurosurgery and Plastic and Reconstructive Surgery, Children's National Health System; Kitware, Inc.; and the Departments of Radiology, Pediatrics, and Biomedical Engineering, George Washington University.

Robert Keating (R)

From the Sheikh Zayed Institute for Pediatric Surgical Innovation and the Departments of Neurosurgery and Plastic and Reconstructive Surgery, Children's National Health System; Kitware, Inc.; and the Departments of Radiology, Pediatrics, and Biomedical Engineering, George Washington University.

Gary F Rogers (GF)

From the Sheikh Zayed Institute for Pediatric Surgical Innovation and the Departments of Neurosurgery and Plastic and Reconstructive Surgery, Children's National Health System; Kitware, Inc.; and the Departments of Radiology, Pediatrics, and Biomedical Engineering, George Washington University.

Marius George Linguraru (MG)

From the Sheikh Zayed Institute for Pediatric Surgical Innovation and the Departments of Neurosurgery and Plastic and Reconstructive Surgery, Children's National Health System; Kitware, Inc.; and the Departments of Radiology, Pediatrics, and Biomedical Engineering, George Washington University.

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