Association of Left Atrial Enlargement and Atrial Fibrillation With Cognitive Function and Decline: The ARIC-NCS.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
03 12 2019
Historique:
entrez: 27 11 2019
pubmed: 27 11 2019
medline: 8 1 2021
Statut: ppublish

Résumé

Background Atrial fibrillation (AF) is associated with cognitive decline. Whether left atrial enlargement (LAE), a critical substrate for AF, is also associated is less well established. Therefore, we assessed the association of LAE and AF with cognitive decline in the ARIC-NCS (Atherosclerosis Risk in Communities Neurocognitive Study). Methods and Results Participants (n=3391; mean age, 75±5 years; 59% women) underwent cognitive tests and 2-dimensional echocardiograms at visit 5 (2011-2013) and follow-up cognitive tests at visit 6 (2016-2017). LAE was defined as left atrium volume index ≥34 mL/m

Identifiants

pubmed: 31766970
doi: 10.1161/JAHA.119.013197
pmc: PMC6912953
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e013197

Subventions

Organisme : NHLBI NIH HHS
ID : U01 HL096812
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL126637
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK089174
Pays : United States
Organisme : American Heart Association-American Stroke Association
ID : 16EIA26410001
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL096902
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL070825
Pays : United States
Organisme : NHLBI NIH HHS
ID : K24 HL148521
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL135008
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL096899
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL141288
Pays : United States
Organisme : NHLBI NIH HHS
ID : K08 HL116792
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL096917
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL096814
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL143224
Pays : United States

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Auteurs

Michael J Zhang (MJ)

Cardiovascular Division Department of Medicine University of Minnesota Medical School Minneapolis MN.

Faye L Norby (FL)

Division of Epidemiology and Community Health School of Public Health University of Minnesota Minneapolis MN.

Pamela L Lutsey (PL)

Division of Epidemiology and Community Health School of Public Health University of Minnesota Minneapolis MN.

Thomas H Mosley (TH)

The MIND Center, University of Mississippi Medical Center Jackson MS.

Rebecca J Cogswell (RJ)

Cardiovascular Division Department of Medicine University of Minnesota Medical School Minneapolis MN.

Suma H Konety (SH)

Cardiovascular Division Department of Medicine University of Minnesota Medical School Minneapolis MN.

Tze-Fan Chao (TF)

Division of Cardiology Department of Medicine Taipei Veterans General Hospital Taipei Taiwan.

Amil M Shah (AM)

Department of Medicine Brigham and Women's Hospital Boston MA.

Scott D Solomon (SD)

Department of Medicine Brigham and Women's Hospital Boston MA.

Alvaro Alonso (A)

Department of Epidemiology Rollins School of Public Health Emory University Atlanta GA.

Lin Y Chen (LY)

Cardiovascular Division Department of Medicine University of Minnesota Medical School Minneapolis MN.

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Classifications MeSH