Risk of Thyroid Cancer in 1,504 Patients Referred for Thyroid Surgery with Assumed Benign Histology.
Benign lesion
Fine-needle aspiration
Thyroid cancer
Thyroid cytology
Thyroid surgery
Journal
European thyroid journal
ISSN: 2235-0640
Titre abrégé: Eur Thyroid J
Pays: England
ID NLM: 101604579
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
27
11
2018
revised:
16
04
2019
entrez:
27
11
2019
pubmed:
27
11
2019
medline:
27
11
2019
Statut:
ppublish
Résumé
The aims of this study were to report the risk of thyroid malignancy in cases of either benign fine-needle aspiration (FNA) or without FNA performed, and to investigate possible predictive factors for thyroid malignancy in a population with recent moderately low iodine intake. All patients referred for thyroid surgery in a tertiary cancer centre between 2000 and 2016 were included ( The malignancy risk was 7.6% (58/764) in group 1 and 6.8% (50/740) in group 2. Patients with T2-4 tumours constituted 2.2% (33/1,504). In the combined groups, ultrasound verified that solitary solid tumour was predictive for malignancy (p = 0.01 by χ The risk of malignancy of 7.6% and 6.8% was high, considering that patients with malignant FNA, suspicious FNA, or clinical findings indicating malignancy were excluded, and 2.2% of these malignancies were stages T2-4. In cases with solitary solid tumour on ultrasound, the risk of malignancy should not be ignored, even with benign FNA.
Identifiants
pubmed: 31768335
doi: 10.1159/000500539
pii: etj-0008-0246
pmc: PMC6873058
doi:
Types de publication
Journal Article
Langues
eng
Pagination
246-255Informations de copyright
Copyright © 2019 by S. Karger AG, Basel.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to declare.
Références
J Laryngol Otol. 2016 May;130(S2):S150-S160
pubmed: 27841128
Thyroid. 2013 Sep;23(9):1159-64
pubmed: 23427917
Dan Med J. 2017 Feb;64(2):
pubmed: 28157060
Eur Thyroid J. 2012 Jul;1(2):110-7
pubmed: 24783005
PLoS One. 2017 Oct 12;12(10):e0186242
pubmed: 29023564
J Cancer Epidemiol. 2013;2013:965212
pubmed: 23737785
Eur J Endocrinol. 2007 Mar;156(3):303-8
pubmed: 17322489
Eur Thyroid J. 2017 Sep;6(5):276-280
pubmed: 29071241
Front Oncol. 2017 Apr 10;7:53
pubmed: 28443243
Ann Surg. 2007 Nov;246(5):714-20
pubmed: 17968160
Head Neck. 2008 Sep;30(9):1246-52
pubmed: 18528906
Thyroid. 2018 Jan;28(1):23-31
pubmed: 28629253
World J Surg. 2014 Mar;38(3):614-21
pubmed: 24081539
Thyroid. 2015 Jan;25(1):78-84
pubmed: 25368981
Arq Bras Endocrinol Metabol. 2014 Dec;58(9):933-8
pubmed: 25627049
BMJ Case Rep. 2015 May 06;2015:null
pubmed: 25948842
Int J Cancer. 2012 Nov 15;131(10):2360-6
pubmed: 22337133
Langenbecks Arch Surg. 2010 Feb;395(2):127-32
pubmed: 19296123
Arch Surg. 2009 Jul;144(7):649-55
pubmed: 19620545
Thyroid. 2005 Mar;15(3):274-8
pubmed: 15785247
Eur Thyroid J. 2017 Sep;6(5):225-237
pubmed: 29167761
Thyroid. 2016 Jan;26(1):1-133
pubmed: 26462967
Clin Endocrinol (Oxf). 2000 Aug;53(2):161-9
pubmed: 10931096
Cancer Epidemiol. 2018 Aug;55:81-87
pubmed: 29852396
Thyroid. 2007 Nov;17(11):1061-6
pubmed: 17910525
Lancet Diabetes Endocrinol. 2016 Nov;4(11):933-942
pubmed: 27550849
Clin Endocrinol (Oxf). 2008 Jun;68(6):996-1001
pubmed: 18031322
Eur Arch Otorhinolaryngol. 2014 May;271(5):1163-70
pubmed: 23775302