Perioperative Management of Pancreaticoduodenectomy: Avoiding Admission to the Intensive Care Unit.
Outcome
Pancreatic cancer
Pancreaticoduodenectomy
Journal
Gastrointestinal tumors
ISSN: 2296-3774
Titre abrégé: Gastrointest Tumors
Pays: Switzerland
ID NLM: 101644585
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
13
06
2019
accepted:
23
08
2019
entrez:
27
11
2019
pubmed:
27
11
2019
medline:
27
11
2019
Statut:
ppublish
Résumé
With the advancement in surgical expertise at high-volume centers and advances in perioperative management, pancreaticoduodenectomy is becoming safer and remains the gold standard for treating periampullary pathologies. We describe our experience in optimizing perioperative management in order to avoid admission to the intensive care unit and improve outcomes. Retrospective data were collected on 370 surgical patients who underwent a pancreaticoduodenectomy between the years 1994 and 2016. Of the 370 patients, 200 operated between 2009 and 2016 did not require intensive care admission, blood transfusion, or central line insertion. The results were compared between different time intervals: before the year 1998, between the years 1998 and 2008, and between the years 2009 and 2016. The median blood loss dropped from 800 to 400 to 300 mL, respectively. The median operative time also dropped from 360 to 335 to 215 min, respectively. In addition, the median length of hospital stay decreased from 25 to 16 to 7 days, respectively. With the centralization of pancreaticoduodenectomy in high-volume centers and with specialized surgeons performing the surgery, there is a significant decrease in the onset of postoperative complications with a lesser need for blood transfusions and, subsequently, better recovery of patients without the need for intensive care unit admission.
Identifiants
pubmed: 31768354
doi: 10.1159/000502887
pii: gat-0006-0108
pmc: PMC6873035
doi:
Types de publication
Journal Article
Langues
eng
Pagination
108-115Informations de copyright
Copyright © 2019 by S. Karger AG, Basel.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to declare.
Références
Surgery. 1999 Mar;125(3):250-6
pubmed: 10076608
Arch Surg. 2010 Jul;145(7):634-40
pubmed: 20644125
Int J Surg. 2015 Sep;21 Suppl 1:S68-71
pubmed: 26122590
Ann Surg. 2015 Aug;262(2):e37-9
pubmed: 26164432
J Surg Res. 2007 May 1;139(1):22-9
pubmed: 17292419
ANZ J Surg. 2001 Sep;71(9):511-5
pubmed: 11527259
J Gastrointest Surg. 2001 Jan-Feb;5(1):21-6
pubmed: 11309644
World J Surg. 2003 Mar;27(3):324-9
pubmed: 12607060
J Gastrointest Surg. 2008 Mar;12(3):442-9
pubmed: 18157583
Biochim Biophys Acta. 2014 Jan;1845(1):42-52
pubmed: 24295567
J Gastrointest Surg. 2006 Nov;10(9):1199-210; discussion 1210-1
pubmed: 17114007
Ann Surg. 2006 Dec;244(6):931-7; discussion 937-9
pubmed: 17122618
Scand J Surg. 2017 Mar;106(1):54-61
pubmed: 27130378
Biomed Res Int. 2014;2014:641239
pubmed: 24900974
Br J Surg. 2008 Mar;95(3):357-62
pubmed: 17933001
Int J Surg. 2016 Aug;32:116-22
pubmed: 27373194
Hepatogastroenterology. 2014 Jan-Feb;61(129):203-7
pubmed: 24895821
J Gastroenterol Hepatol. 2014;29(7):1360-70
pubmed: 24650171