Comparison of the histopathological characteristics of large colorectal laterally spreading tumors according to growth pattern.

biological malignancy growth pattern histopathological characteristics large colorectal laterally spreading tumors

Journal

Journal of the anus, rectum and colon
ISSN: 2432-3853
Titre abrégé: J Anus Rectum Colon
Pays: Japan
ID NLM: 101718055

Informations de publication

Date de publication:
2019
Historique:
received: 02 11 2018
accepted: 05 08 2019
entrez: 27 11 2019
pubmed: 27 11 2019
medline: 27 11 2019
Statut: epublish

Résumé

Colorectal laterally spreading tumors (LSTs) are widely recognized owing to their structural characteristics. This study aims to clarify the histopathological characteristics of large colorectal LSTs according to growth pattern. We studied 297 colorectal LSTs measuring ≥20 mm in diameter. The LSTs were classified into four types: granular homogenous type (LST-G-H), granular nodular mixed type (LST-G-M), non-granular flat elevated type (LST-NG-F), and non-granular pseudo-depressed type (LST-NG-PD). Retrospectively collected data were examined to compare the histopathological characteristics of LSTs according to the growth pattern. LST-G-M lesions (142 lesions) were most common, followed by LST-NG-F (74 lesions), LST-G-H (61 lesions), and LST-NG-PD (20 lesions). The mean tumor diameter of LST-G lesions (38.5 ± 17.2 mm) was significantly greater than that of LST-NG lesions (26.3 ± 7.0 mm, The biological malignancy of colorectal LSTs differs considerably depending on the growth pattern even among large lesions and therefore should be considered when selecting treatment regimens.

Identifiants

pubmed: 31768465
doi: 10.23922/jarc.2018-036
pmc: PMC6845292
doi:

Types de publication

Journal Article

Langues

eng

Pagination

152-159

Informations de copyright

Copyright © 2019 by The Japan Society of Coloproctology.

Déclaration de conflit d'intérêts

Conflicts of Interest There are no conflicts of interest.

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Auteurs

Tomoya Saito (T)

Department of Gastroenterology, Kitasato University, School of Medicine, Sagamihara, Japan.

Kiyonori Kobayashi (K)

Research and Development Center for New Medical Frontiers, Kitasato University, School of Medicine, Sagamihara, Japan.

Miwa Sada (M)

Department of Gastroenterology, Kitasato University, School of Medicine, Sagamihara, Japan.

Yasuhiro Matsumoto (Y)

Department of Gastroenterology, Kitasato University, School of Medicine, Sagamihara, Japan.

Miyuki Mukae (M)

Department of Gastroenterology, Kitasato University, School of Medicine, Sagamihara, Japan.

Kana Kawagishi (K)

Department of Gastroenterology, Kitasato University, School of Medicine, Sagamihara, Japan.

Kaoru Yokoyama (K)

Department of Gastroenterology, Kitasato University, School of Medicine, Sagamihara, Japan.

Wasaburo Koizumi (W)

Department of Gastroenterology, Kitasato University, School of Medicine, Sagamihara, Japan.

Makoto Saegusa (M)

Department of Pathology, Kitasato University, School of Medicine, Sagamihara, Japan.

Yoshitaka Murakami (Y)

Department of Medical Statistics, Toho University, School of Medicine, Tokyo, Japan.

Classifications MeSH