A Pilot Randomized Clinical Trial of a Multidisciplinary Intervention for Encopresis in Children with Autism Spectrum Disorder.


Journal

Journal of autism and developmental disorders
ISSN: 1573-3432
Titre abrégé: J Autism Dev Disord
Pays: United States
ID NLM: 7904301

Informations de publication

Date de publication:
Mar 2020
Historique:
pubmed: 27 11 2019
medline: 1 7 2020
entrez: 27 11 2019
Statut: ppublish

Résumé

Children with autism spectrum disorder (ASD) are often delayed in achieving bowel continence, resulting in negative outcomes. In this pilot trial, 20 children with ASD and encopresis were randomly assigned to multidisciplinary intervention for encopresis (MIE; n = 10) or a waitlist control group (n = 10). The MIE group was treated for constipation and received a 10-day behavioral intervention that utilized suppositories to produce predictable bowel movements that were reinforced. Caregivers were trained to implement the intervention. Results support the feasibility of clinical trials of MIE, with high enrolment, competition, attendance, and caregiver acceptability. Preliminary outcomes were positive, with six of 10 in the MIE group achieving continence by the end of treatment compared to 0 in the control group (p = 0.005).Registered at clinicaltrials.gov (https://clinicaltrials.gov); ID: NCT02383732.

Identifiants

pubmed: 31768718
doi: 10.1007/s10803-019-04305-5
pii: 10.1007/s10803-019-04305-5
doi:

Substances chimiques

Gastrointestinal Agents 0
Suppositories 0

Banques de données

ClinicalTrials.gov
['NCT02383732']

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

757-765

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Auteurs

Joanna Lomas Mevers (J)

Division of Autism & Related Disabilities, Emory University School of Medicine, Atlanta, USA. Joanna.lomasmevers@choa.org.
Division of Autism & Related Disabilities, Marcus Autism Center, 1920 Briarcliff Rd., Atlanta, GA, 30329, USA. Joanna.lomasmevers@choa.org.
Division of Autism & Related Disabilities, Children's Healthcare of Atlanta, Atlanta, USA. Joanna.lomasmevers@choa.org.

Nathan A Call (NA)

Division of Autism & Related Disabilities, Emory University School of Medicine, Atlanta, USA.
Division of Autism & Related Disabilities, Marcus Autism Center, 1920 Briarcliff Rd., Atlanta, GA, 30329, USA.
Division of Autism & Related Disabilities, Children's Healthcare of Atlanta, Atlanta, USA.

Kristina R Gerencser (KR)

Division of Autism & Related Disabilities, Emory University School of Medicine, Atlanta, USA.
Division of Autism & Related Disabilities, Marcus Autism Center, 1920 Briarcliff Rd., Atlanta, GA, 30329, USA.
Division of Autism & Related Disabilities, Children's Healthcare of Atlanta, Atlanta, USA.

Mindy Scheithauer (M)

Division of Autism & Related Disabilities, Emory University School of Medicine, Atlanta, USA.
Division of Autism & Related Disabilities, Marcus Autism Center, 1920 Briarcliff Rd., Atlanta, GA, 30329, USA.
Division of Autism & Related Disabilities, Children's Healthcare of Atlanta, Atlanta, USA.

Sarah J Miller (SJ)

Children's Hospital New Orleans, New Orleans, USA.

Colin Muething (C)

Division of Autism & Related Disabilities, Emory University School of Medicine, Atlanta, USA.
Division of Autism & Related Disabilities, Marcus Autism Center, 1920 Briarcliff Rd., Atlanta, GA, 30329, USA.
Division of Autism & Related Disabilities, Children's Healthcare of Atlanta, Atlanta, USA.

Shannon Hewett (S)

Division of Autism & Related Disabilities, Marcus Autism Center, 1920 Briarcliff Rd., Atlanta, GA, 30329, USA.

Courtney McCracken (C)

Division of Autism & Related Disabilities, Emory University School of Medicine, Atlanta, USA.

Lawrence Scahill (L)

Division of Autism & Related Disabilities, Emory University School of Medicine, Atlanta, USA.

Barbara O McElhanon (BO)

Division of Autism & Related Disabilities, Emory University School of Medicine, Atlanta, USA.
Division of Autism & Related Disabilities, Children's Healthcare of Atlanta, Atlanta, USA.

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