Sigma-1 Receptor Agonist Amitriptyline Inhibits Store-Dependent Ca

Amitriptyline / pharmacology Animals Calcium / metabolism Calcium Signaling / drug effects Indoles / pharmacology Ion Transport / drug effects Macrophages, Peritoneal / metabolism Rats Rats, Wistar Receptors, sigma / agonists Thapsigargin / pharmacology Sigma-1 Receptor

Journal

Doklady. Biochemistry and biophysics
ISSN: 1608-3091
Titre abrégé: Dokl Biochem Biophys
Pays: United States
ID NLM: 101126895

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 08 02 2019
entrez: 27 11 2019
pubmed: 27 11 2019
medline: 20 3 2020
Statut: ppublish

Résumé

Using Fura-2AM microfluorimetry, we have shown for the first time that sigma-1 receptor agonist-tricyclic antidepressant amitriptyline-significantly inhibits store-dependent Ca

Identifiants

DOI: 10.1134/S1607672919050041 PMID: 31768847
pubmed: 31768847
doi: 10.1134/S1607672919050041
pii: 10.1134/S1607672919050041
doi:

Substances chimiques

Indoles 0
Receptors, sigma 0
Amitriptyline 1806D8D52K
Thapsigargin 67526-95-8
Calcium SY7Q814VUP
cyclopiazonic acid X9TLY4580Z

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

307-310

Références

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pubmed: 17471183
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pubmed: 3838314
Curr Neuropharmacol. 2018;16(1):97-116
pubmed: 28554311
Physiol Rev. 2015 Oct;95(4):1383-436
pubmed: 26400989
J Cell Biol. 2016 Apr 11;213(1):65-79
pubmed: 27069021
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pubmed: 26056947
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pubmed: 26591064
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pubmed: 11867616
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pubmed: 21427517
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pubmed: 12234126
Biochem J. 2016 Jan 1;473(1):1-5
pubmed: 26467159

Auteurs

Z I Krutetskaya (ZI)

St. Petersburg State University, St. Petersburg, Russia. z.krutetskaya@spbu.ru.

L S Milenina (LS)

St. Petersburg State University, St. Petersburg, Russia.

V G Antonov (VG)

St. Petersburg State University, St. Petersburg, Russia.

A D Nozdrachev (AD)

St. Petersburg State University, St. Petersburg, Russia. a.d.nozdrachev@mail.ru.
Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia. a.d.nozdrachev@mail.ru.

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Classifications MeSH

questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Benzocycloheptènes › Dibenzocycloheptènes › Amitriptyline › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Eucaryotes › Animaux › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Systèmes de seconds messagers › Signalisation calcique › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Indoles › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Métabolisme › Transport biologique › Transport des ions › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Macrophages péritonéaux › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur aux neuropeptides › Récepteurs aux opioïdes › Récepteur sigma › Sigma-1 Receptor Agonist Amitriptyline...
questionsmedicales.fr › Composés polycycliques › Sesquiterpènes polycycliques › Sesquiterpènes de type eudesmane › Sesquiterpènes de type guaïane › Thapsigargine › Sigma-1 Receptor Agonist Amitriptyline...