Advanced glycation end products are associated with sarcopenia in older women: aging marker dynamics.


Journal

Journal of women & aging
ISSN: 1540-7322
Titre abrégé: J Women Aging
Pays: England
ID NLM: 8916635

Informations de publication

Date de publication:
Historique:
pubmed: 27 11 2019
medline: 5 10 2021
entrez: 27 11 2019
Statut: ppublish

Résumé

The aim of this study was to determine whether advanced glycation end products (AGEs) revealed by skin autofluorescence (SAF), serum and urine pentosidine level, and serum homocysteine level can serve as a biomarker for sarcopenia in older women. The participants were 70 elderly women. The AGEs pentosidine, homocysteine, and SAF were measured as aging markers. This study shows that among the biomarkers for aging, serum pentosidine correlates with a loss of appendicular lean mass and can serve as a biomarker for sarcopenia. Moreover, SAF and homocysteine values exhibited a positive correlation with age and correlated with each other.

Identifiants

pubmed: 31770087
doi: 10.1080/08952841.2019.1697161
doi:

Substances chimiques

Biomarkers 0
Glycation End Products, Advanced 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

328-340

Auteurs

Yawara Eguchi (Y)

Department of Orthopaedic Surgery, Shimoshizu National Hospital, Yotsukaido, Japan.

Toru Toyoguchi (T)

Department of Orthopaedic Surgery, Chiba Qiball clinic, Chuo-ku, Japan.

Kazuhide Inage (K)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Kazuki Fujimoto (K)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Sumihisa Orita (S)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Miyako Suzuki (M)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Hirohito Kanamoto (H)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Koki Abe (K)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Masaki Norimoto (M)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Tomotaka Umimura (T)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Masao Koda (M)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Takeo Furuya (T)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Yasuchika Aoki (Y)

Department of Orthopaedic Surgery, Eastern Chiba Medical Center, Togane, Japan.

Junichi Nakamura (J)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Tsutomu Akazawa (T)

Department of Orthopaedic Surgery, St. Marianna University School of Medicine, Miyamae-ku, Kawasaki, Japan.

Kazuhisa Takahashi (K)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

Seiji Ohtori (S)

Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Japan.

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