Effects of Pulmonary Hypertension on Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease.
Cardiopulmonary exercise test
Chronic obstructive pulmonary disease
Enfermedad pulmonar obstructiva crónica
Exercise tolerance
Hipertensión pulmonar
Prueba de ejercicio cardiopulmonar
Prueba de marcha de seis minutos
Pulmonary hypertension
Six-minute walk test
Tolerancia al ejercicio
Journal
Archivos de bronconeumologia
ISSN: 2173-5751
Titre abrégé: Arch Bronconeumol (Engl Ed)
Pays: Spain
ID NLM: 101777538
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
received:
01
08
2019
revised:
17
09
2019
accepted:
11
10
2019
pubmed:
28
11
2019
medline:
25
6
2021
entrez:
28
11
2019
Statut:
ppublish
Résumé
The impact of pulmonary hypertension (PH) on exercise tolerance in chronic obstructive pulmonary disease (COPD) has not been fully elucidated. It is necessary to characterize pulmonary hemodynamics in patients with moderate to severe COPD in order to improve their management. The aim of the study was to determine whether in COPD the presence of PH is associated with reduced exercise tolerance in a cohort of stable COPD patients. Cross-sectional analysis of 174 COPD patients clinically stable: 109 without PH and 65 with PH (COPD-PH). We assessed socio-demographic data, lung function, quality of life, dyspnea, cardiopulmonary exercise testing (CPET), constant workload endurance time (CWET), and six-minute walk test (6MWT). We elaborated a logistic regression model to explore the impact of PH on exercise capacity in COPD patients. COPD-PH patients showed lower exercise capacity both at maximal (CPET) (43(20) versus 68(27) Watts and 50(19)% versus 71(18)% predicted peak oxygen consumption (VO The presence of PH is an independent factor that impairs exercise capacity in COPD.
Identifiants
pubmed: 31771920
pii: S0300-2896(19)30407-7
doi: 10.1016/j.arbres.2019.10.015
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
spa
Sous-ensembles de citation
IM
Pagination
499-505Informations de copyright
Copyright © 2019 The Author(s). Publicado por Elsevier España, S.L.U. All rights reserved.