Epidemiology of Alzheimer's Disease and Dementia in Arab Countries: A Systematic Review.


Journal

Behavioural neurology
ISSN: 1875-8584
Titre abrégé: Behav Neurol
Pays: Netherlands
ID NLM: 8914585

Informations de publication

Date de publication:
2019
Historique:
received: 26 01 2019
revised: 25 05 2019
accepted: 16 09 2019
entrez: 28 11 2019
pubmed: 28 11 2019
medline: 28 4 2020
Statut: epublish

Résumé

Contrary to popular belief, the condition of dementia is not an actual discrete disease, but rather a group of symptoms, most notable of which is the disturbance of memory and social ability, often severe enough to impair daily functioning. As a result, it has been a major cause of functional deterioration among varying populations in the world. This study is aimed at reviewing the epidemiology of dementia in Arab countries in terms of its prevalence, distribution, and risk factors. A systematic literature review was conducted using articles published in PubMed, Embase, Scopus, and other local journals between 1990 and 2018. After applying the inclusion and exclusion criteria, a total of 18 studies were concluded to be eligible for the review. Prevalence studies demonstrated that dementia is indeed a prevalent condition in Arab countries, ranging between 1.1% and 2.3% among age groups of 50 years and older, as well as between 13.5% and 18.5% among age groups of 80 years and above. However, these results are not different from those of many other countries in the world. Moreover, prevalence was found to vary depending on sociodemographic characteristics. Major risk factors of dementia included hypertension, low income, and low education, while the risk of developing dementia is increased by obesity, diabetes mellitus, and cardiovascular risk factors. Despite the growing evidence regarding the epidemiological distribution and determinants of dementia worldwide, studies from the Arab region remain scarce. This systematic review highlights the need for population-based studies to provide necessary information for developing preventive and curative strategies specific to the Arab region.

Sections du résumé

BACKGROUND/OBJECTIVES OBJECTIVE
Contrary to popular belief, the condition of dementia is not an actual discrete disease, but rather a group of symptoms, most notable of which is the disturbance of memory and social ability, often severe enough to impair daily functioning. As a result, it has been a major cause of functional deterioration among varying populations in the world. This study is aimed at reviewing the epidemiology of dementia in Arab countries in terms of its prevalence, distribution, and risk factors.
METHODS METHODS
A systematic literature review was conducted using articles published in PubMed, Embase, Scopus, and other local journals between 1990 and 2018. After applying the inclusion and exclusion criteria, a total of 18 studies were concluded to be eligible for the review.
RESULTS RESULTS
Prevalence studies demonstrated that dementia is indeed a prevalent condition in Arab countries, ranging between 1.1% and 2.3% among age groups of 50 years and older, as well as between 13.5% and 18.5% among age groups of 80 years and above. However, these results are not different from those of many other countries in the world. Moreover, prevalence was found to vary depending on sociodemographic characteristics. Major risk factors of dementia included hypertension, low income, and low education, while the risk of developing dementia is increased by obesity, diabetes mellitus, and cardiovascular risk factors. Despite the growing evidence regarding the epidemiological distribution and determinants of dementia worldwide, studies from the Arab region remain scarce.
CONCLUSION CONCLUSIONS
This systematic review highlights the need for population-based studies to provide necessary information for developing preventive and curative strategies specific to the Arab region.

Identifiants

pubmed: 31772681
doi: 10.1155/2019/3935943
pmc: PMC6854962
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

3935943

Informations de copyright

Copyright © 2019 Ashraf El-Metwally et al.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest regarding the publication of this article.

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Auteurs

Ashraf El-Metwally (A)

College of Public Health and Health Informatics, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Paivi Toivola (P)

King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Mashael Al-Rashidi (M)

Saudi Food and Drug Authority, Riyadh, Saudi Arabia.

Shanila Nooruddin (S)

Dow University of Health Sciences, Karachi, Pakistan.

Munazza Jawed (M)

Dow University of Health Sciences, Karachi, Pakistan.

Raghad AlKanhal (R)

King Abdullah International Medical Research Center/King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.

Hira Abdul Razzak (HA)

Ministry of Health and Prevention, Dubai, UAE.

Nada Albawardi (N)

Epidemiology and Biostatistics Section, Health Sciences Research Centre, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.

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Classifications MeSH