MR-Guided Percutaneous Intradiscal Thermotherapy (MRgPIT): Evaluation of a New Technique for the Treatment of Degenerative Disc Disease in Cadaveric Lumbar Spine.


Journal

Cardiovascular and interventional radiology
ISSN: 1432-086X
Titre abrégé: Cardiovasc Intervent Radiol
Pays: United States
ID NLM: 8003538

Informations de publication

Date de publication:
Mar 2020
Historique:
received: 14 06 2019
accepted: 19 11 2019
pubmed: 28 11 2019
medline: 6 10 2020
entrez: 28 11 2019
Statut: ppublish

Résumé

Evaluation of MR feasibility and real-time control of an innovative thermoablative applicator for intradiscal thermotherapy and histological analysis of laser annuloplasty in human ex vivo intervertebral discs. We evaluated a new MR-compatible applicator system for MR-guided percutaneous intradiscal thermotherapy (MRgPIT) in an open 1.0-T MRI-system. Needle artefacts and contrast-to-noise ratios (CNR) of six interactive sequences (PD-, T1-, T2w TSE, T1-, T2w GRE, bSSFP) with varying echo-times (TE) and needle orientations to the main magnetic field (B In vitro, we found optimal needle artefacts of 1.5-5 mm for the PDw TSE sequence in all angles of the applicator system to B Real-time MR-guided positioning of the MRgPIT-applicator in cadaveric intervertebral disc is feasible and precise using fast TSE sequence designs. Laser-induced denaturation of collagen in the dorsal annulus fibrosus proved to be accurate.

Identifiants

pubmed: 31773189
doi: 10.1007/s00270-019-02382-8
pii: 10.1007/s00270-019-02382-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

505-513

Auteurs

T Leidenberger (T)

Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany. tilman.leidenberger@med.uni-heidelberg.de.

A Winkel (A)

R&D Interventional Instruments, Invivo Corporation, Gainesville, FL, USA.

C Philipp (C)

Center for Laser Medicine, Evangelical Elisabeth Clinic, Berlin, Germany.

J Rump (J)

Biotronik SE & Co KG, Berlin, Germany.

M De Bucourt (M)

Department of Radiology, Charité, Humboldt-University, Berlin, Germany.

G Böning (G)

Department of Radiology, Charité, Humboldt-University, Berlin, Germany.

U Teichgräber (U)

Department of Radiology, Friedrich-Schiller-University, Jena, Germany.

F Streitparth (F)

Department of Radiology, Ludwig Maximilian University, Munich, Germany.

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Classifications MeSH