FACT caught in the act of manipulating the nucleosome.

Cell Cycle Proteins / chemistry Cryoelectron Microscopy DNA / chemistry DNA-Binding Proteins / chemistry High Mobility Group Proteins / chemistry Histones / chemistry Humans Models, Molecular Nucleosomes / chemistry Protein Structure, Quaternary Protein Structure, Tertiary Transcription Factors / chemistry Transcriptional Elongation Factors / chemistry

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
01 2020
Historique:
received: 11 07 2019
accepted: 07 11 2019
pubmed: 28 11 2019
medline: 28 4 2020
entrez: 28 11 2019
Statut: ppublish

Résumé

The organization of genomic DNA into nucleosomes profoundly affects all DNA-related processes in eukaryotes. The histone chaperone known as 'facilitates chromatin transcription' (FACT

Identifiants

DOI: 10.1038/s41586-019-1820-0 PMID: 31775157 PMC: PMC7441595
pubmed: 31775157
doi: 10.1038/s41586-019-1820-0
pii: 10.1038/s41586-019-1820-0
pmc: PMC7441595
mid: NIHMS1541986
doi:

Substances chimiques

Cell Cycle Proteins 0
DNA-Binding Proteins 0
High Mobility Group Proteins 0
Histones 0
Nucleosomes 0
SSRP1 protein, human 0
SUPT16H protein, human 0
Transcription Factors 0
Transcriptional Elongation Factors 0
DNA 9007-49-2

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

426-431

Subventions

Organisme : NCRR NIH HHS
ID : P41 RR001209
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM133751
Pays : United States
Organisme : NIH HHS
ID : S10 OD019994
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NIGMS NIH HHS
ID : GM133751
Pays : United States
Organisme : NIGMS NIH HHS
ID : P41 GM103310
Pays : United States

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Auteurs

Yang Liu (Y)

Department of Biochemistry, University of Colorado at Boulder, Boulder, CO, USA.

Keda Zhou (K)

Department of Biochemistry, University of Colorado at Boulder, Boulder, CO, USA.

Naifu Zhang (N)

Department of Chemistry and Biochemistry, The University of Texas at Dallas, Dallas, TX, USA.

Hui Wei (H)

National Resource for Automated Molecular Microscopy Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY, USA.

Yong Zi Tan (YZ)

National Resource for Automated Molecular Microscopy Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY, USA.
Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.

Zhening Zhang (Z)

National Resource for Automated Molecular Microscopy Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY, USA.
Biochemistry and Molecular Biophysics Department, Columbia University Medical Center, New York, NY, USA.
Biochemistry and Molecular Biophysics Department, Columbia University Medical Center, New York, NY, USA.

Bridget Carragher (B)

National Resource for Automated Molecular Microscopy Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY, USA.

Clinton S Potter (CS)

National Resource for Automated Molecular Microscopy Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY, USA.

Sheena D'Arcy (S)

Department of Chemistry and Biochemistry, The University of Texas at Dallas, Dallas, TX, USA.

Karolin Luger (K)

Department of Biochemistry, University of Colorado at Boulder, Boulder, CO, USA. karolin.luger@colorado.edu.
Howard Hughes Medical Institute, Chevy Chase, MD, USA. karolin.luger@colorado.edu.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cycle cellulaire › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Cryomicroscopie électronique › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de liaison à l'ADN › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Protéines chromosomiques nonhistones › Protéines HMG › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Histone › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles moléculaires › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Structures de chromosome › Chromatine › Nucléosomes › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure quaternaire des protéines › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure tertiaire des protéines › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › FACT caught in the act of manipulating the nucleosome.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs d'élongation transcriptionnelle › FACT caught in the act of manipulating the nucleosome.