Semaphorin 3E Regulates the Response of Macrophages to Lipopolysaccharide-Induced Systemic Inflammation.

Animals Cells, Cultured Inflammation / chemically induced Lipopolysaccharides / administration & dosage Macrophages / immunology Mice Mice, Knockout Mice, Transgenic Semaphorins / deficiency

Journal

Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R

Informations de publication

Date de publication:
01 01 2020
Historique:
received: 21 12 2018
accepted: 28 10 2019
pubmed: 30 11 2019
medline: 30 7 2020
entrez: 29 11 2019
Statut: ppublish

Résumé

Semaphorin 3E (Sema3E) is a secreted protein that was initially discovered as a neuronal guidance cue. Recent evidence showed that Sema3E plays an essential role in regulating the activities of various immune cells. However, the exact role of Sema3E in macrophage function, particularly during inflammation, is not fully understood. We studied the impact of

Identifiants

DOI: 10.4049/jimmunol.1801514 PMID: 31776203
pubmed: 31776203
pii: jimmunol.1801514
doi: 10.4049/jimmunol.1801514
doi:

Substances chimiques

Lipopolysaccharides 0
Sema3e protein, mouse 0
Semaphorins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

128-136

Informations de copyright

Copyright © 2019 by The American Association of Immunologists, Inc.

Auteurs

Ashfaque Mohammed (A)

Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada.

Ifeoma Okwor (I)

Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada.

Lianyu Shan (L)

Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada.

Chukwunonso Onyilagha (C)

Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada.

Jude E Uzonna (JE)

Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada.

Abdelilah S Gounni (AS)

Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada abdel.gounni@umanitoba.ca.
ORCID: 0000-0003-1265-6560

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Semaphorin 3E Regulates the Response of...
questionsmedicales.fr › Cellules › Cellules cultivées › Semaphorin 3E Regulates the Response of...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Semaphorin 3E Regulates the Response of...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Toxines bactériennes › Endotoxines › Lipopolysaccharides › Semaphorin 3E Regulates the Response of...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Semaphorin 3E Regulates the Response of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Semaphorin 3E Regulates the Response of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Semaphorin 3E Regulates the Response of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Semaphorin 3E Regulates the Response of...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Sémaphorines › Semaphorin 3E Regulates the Response of...