The Influence of Simulated Sunlight on the Inactivation of Influenza Virus in Aerosols.
aerosol
decay
influenza virus
relative humidity
sunlight
Journal
The Journal of infectious diseases
ISSN: 1537-6613
Titre abrégé: J Infect Dis
Pays: United States
ID NLM: 0413675
Informations de publication
Date de publication:
14 01 2020
14 01 2020
Historique:
received:
06
09
2019
accepted:
18
11
2019
pubmed:
30
11
2019
medline:
22
9
2020
entrez:
29
11
2019
Statut:
ppublish
Résumé
Environmental parameters, including sunlight levels, are known to affect the survival of many microorganisms in aerosols. However, the impact of sunlight on the survival of influenza virus in aerosols has not been previously quantified. The present study examined the influence of simulated sunlight on the survival of influenza virus in aerosols at both 20% and 70% relative humidity using an environmentally controlled rotating drum aerosol chamber. Measured decay rates were dependent on the level of simulated sunlight, but they were not significantly different between the 2 relative humidity levels tested. In darkness, the average decay constant was 0.02 ± 0.06 min-1, equivalent to a half-life of 31.6 minutes. However, at full intensity simulated sunlight, the mean decay constant was 0.29 ± 0.09 min-1, equivalent to a half-life of approximately 2.4 minutes. These results are consistent with epidemiological findings that sunlight levels are inversely correlated with influenza transmission, and they can be used to better understand the potential for the virus to spread under varied environmental conditions.
Sections du résumé
BACKGROUND
Environmental parameters, including sunlight levels, are known to affect the survival of many microorganisms in aerosols. However, the impact of sunlight on the survival of influenza virus in aerosols has not been previously quantified.
METHODS
The present study examined the influence of simulated sunlight on the survival of influenza virus in aerosols at both 20% and 70% relative humidity using an environmentally controlled rotating drum aerosol chamber.
RESULTS
Measured decay rates were dependent on the level of simulated sunlight, but they were not significantly different between the 2 relative humidity levels tested. In darkness, the average decay constant was 0.02 ± 0.06 min-1, equivalent to a half-life of 31.6 minutes. However, at full intensity simulated sunlight, the mean decay constant was 0.29 ± 0.09 min-1, equivalent to a half-life of approximately 2.4 minutes.
CONCLUSIONS
These results are consistent with epidemiological findings that sunlight levels are inversely correlated with influenza transmission, and they can be used to better understand the potential for the virus to spread under varied environmental conditions.
Identifiants
pubmed: 31778532
pii: 5645407
doi: 10.1093/infdis/jiz582
doi:
Substances chimiques
Aerosols
0
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
372-378Informations de copyright
© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.