How to approach a patient with parkinsonism - red flags for atypical parkinsonism.

Atypical parkinsonian disorders Lewy body disease Multiple system atrophy Parkinson disease Red flags Supranuclear palsy

Journal

International review of neurobiology
ISSN: 2162-5514
Titre abrégé: Int Rev Neurobiol
Pays: United States
ID NLM: 0374740

Informations de publication

Date de publication:
2019
Historique:
entrez: 30 11 2019
pubmed: 30 11 2019
medline: 2 6 2020
Statut: ppublish

Résumé

Parkinsonism is a clinical syndrome defined by bradykinesia plus rigidity or tremor. Though most commonly encountered in the setting of idiopathic Parkinson's disease, a number of neurodegenerative, structural, metabolic and toxic neurological disorders can result in parkinsonism. Accurately diagnosing the underlying cause of parkinsonism is of both therapeutic and prognostic relevance, especially as we enter the era of disease-modifying treatment trials for neurodegenerative disorders. Being aware of the wide array of potential causes of parkinsonism is of paramount importance for clinicians. In this chapter, we present a pragmatic clinical approach to patients with parkinsonism, specifically focusing on 'red flags', which should alert one to consider diagnoses other than idiopathic Parkinson's disease.

Identifiants

pubmed: 31779810
pii: S0074-7742(19)30087-X
doi: 10.1016/bs.irn.2019.10.001
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-34

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Eoin Mulroy (E)

Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.

Maria Stamelou (M)

Parkinson's Disease and Movement Disorders Department, HYGEIA Hospital, Athens, Greece; Aiginiteion Hospital, First Department of Neurology, University of Athens, Greece; Clinic for Neurology, Philipps University, Marburg, Germany.

Kailash P Bhatia (KP)

Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.

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Classifications MeSH