'Atypical' Parkinson's disease - sporadic.
Classification
MDS-PD criteria
Parkinson's disease
Journal
International review of neurobiology
ISSN: 2162-5514
Titre abrégé: Int Rev Neurobiol
Pays: United States
ID NLM: 0374740
Informations de publication
Date de publication:
2019
2019
Historique:
entrez:
30
11
2019
pubmed:
30
11
2019
medline:
2
6
2020
Statut:
ppublish
Résumé
Parkinson's disease still is a clinical diagnosis. Also, the MDS Clinical Diagnostic Criteria for Parkinson's disease published in 2015 are based on clinical characteristics and were designed codifying the diagnostic process of an expert. The purpose was to support less experienced neurologists to achieve the diagnostic procedure up to the level of an expert. The criteria include both negative and positive properties. However, some features exclude patients with typical Parkinson's disease mainly during their early or late stages. These includes symptoms such as the absence of the combination of typical motor symptoms, the insufficient response to dopaminergic treatment, autonomic dysfunction, dystonia, postural instability or cognitive impairment. This chapter discusses those "atypical" symptom constellations that complicate the differential diagnosis of PD versus atypical parkinsonism and illustrates additional considerations that might be helpful to achieve a correct diagnosis.
Identifiants
pubmed: 31779812
pii: S0074-7742(19)30088-1
doi: 10.1016/bs.irn.2019.10.002
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
195-206Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.