Recent advances in understanding Japanese encephalitis.
JEV
blood brain barrier.
exosome
microglia activation
neuroinflammation
Journal
F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320
Informations de publication
Date de publication:
2019
2019
Historique:
accepted:
07
11
2019
entrez:
30
11
2019
pubmed:
30
11
2019
medline:
4
6
2020
Statut:
epublish
Résumé
Japanese encephalitis (JE) is a clinical manifestation of the brain inflammation caused by JE virus (JEV). This virus imparts permanent neurological damage, thus imposing a heavy burden on public health and society. Neuro-inflammation is the hallmark of JEV infection. The prolonged pro-inflammatory response is due primarily to microglial activation, which eventually leads to severe encephalitis. A continual effort is going on in the scientific community toward an understanding of cellular and molecular factors that are involved in JEV neuro-invasion and inflammatory processes. This review not only gives a comprehensive update on the recent advances on understanding virus structure and mechanisms of pathogenesis but also briefly discusses crucial unresolved issues. We also highlight challenging areas of research that might open new avenues for controlling virus-induced neuro-inflammation.
Identifiants
pubmed: 31781366
doi: 10.12688/f1000research.19693.1
pmc: PMC6854871
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright: © 2019 Banerjee A and Tripathi A.
Déclaration de conflit d'intérêts
No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.
Références
Neurochem Int. 2011 Feb;58(2):234-42
pubmed: 21167894
J Virol. 2017 Oct 13;91(21):
pubmed: 28814523
Neuroscience. 2019 May 1;405:148-157
pubmed: 29660443
F1000Res. 2017 Mar 13;6:259
pubmed: 28357054
Nucleic Acid Ther. 2018 Dec;28(6):357-365
pubmed: 30457923
Sci Signal. 2017 Feb 14;10(466):eaaf5185
pubmed: 28196914
J Neurochem. 2019 May;149(4):518-534
pubmed: 30556910
Stem Cell Res Ther. 2015 Sep 29;6:187
pubmed: 26420371
J Virol. 2016 Apr 14;90(9):4780-4795
pubmed: 26937036
J Immunol. 2019 Oct 15;203(8):2222-2238
pubmed: 31527198
Infect Immun. 1981 Oct;34(1):26-9
pubmed: 6271682
Indian Pediatr. 2013 Dec;50(12):1095-108
pubmed: 24413503
J Neuroinflammation. 2018 Aug 25;15(1):238
pubmed: 30144801
Nat Rev Neurol. 2018 Apr 26;14(5):298-313
pubmed: 29697099
J Virol. 2018 May 29;92(12):
pubmed: 29593046
Sci Rep. 2016 Jun 10;6:27685
pubmed: 27282499
Sci Rep. 2018 Aug 6;8(1):11784
pubmed: 30082709
J Gen Virol. 1989 Feb;70 ( Pt 2):461-5
pubmed: 2543749
Viruses. 2019 Jan 21;11(1):
pubmed: 30669601
Viruses. 2018 Nov 14;10(11):
pubmed: 30441759
J Virol. 2014 May;88(9):4798-810
pubmed: 24522920
Front Microbiol. 2017 Apr 11;8:651
pubmed: 28443089
Eur J Immunol. 2013 Jul;43(7):1789-98
pubmed: 23568450
Virol J. 2014 Jan 23;11:10
pubmed: 24456815
PLoS Negl Trop Dis. 2017 Feb 2;11(2):e0005329
pubmed: 28151989
J Neuroinflammation. 2014 May 29;11:97
pubmed: 24885259
J Neuroinflammation. 2018 May 28;15(1):168
pubmed: 29807527
Front Cell Infect Microbiol. 2019 Aug 09;9:291
pubmed: 31448245
J Neuroinflammation. 2014 Feb 01;11:24
pubmed: 24485101
Eur J Immunol. 2012 Oct;42(10):2655-66
pubmed: 22706912
Front Neurosci. 2019 Jan 24;13:14
pubmed: 30733666
Immune Netw. 2017 Jun;17(3):192-200
pubmed: 28680381
J Immunol. 2010 Aug 1;185(3):1429-41
pubmed: 20581148
Molecules. 2018 Dec 18;23(12):null
pubmed: 30567313
Vector Borne Zoonotic Dis. 2019 Jan;19(1):35-44
pubmed: 30207876
Hum Vaccin Immunother. 2017 Jun 3;13(6):1-18
pubmed: 28301270
J Virol. 2013 Jan;87(1):148-62
pubmed: 23055570
EBioMedicine. 2019 Jan;39:332-347
pubmed: 30527622
J Virol. 2017 Feb 28;91(6):
pubmed: 28053106
J Infect Dis. 2014 Sep 15;210(6):875-89
pubmed: 24652493
J Neurochem. 2014 Apr;129(1):143-54
pubmed: 24236890
J Virol. 2018 Mar 14;92(7):
pubmed: 29343583
Front Cell Neurosci. 2016 May 02;10:109
pubmed: 27199663
J Virol. 2012 Feb;86(4):2337-46
pubmed: 22156523
J Virol. 2018 Nov 27;92(24):
pubmed: 30282716
Sci Rep. 2016 Feb 03;6:20263
pubmed: 26838068
J Virol. 2015 May;89(10):5602-14
pubmed: 25762733
Autophagy. 2014 Sep;10(9):1637-51
pubmed: 25046112
Pharmaceutics. 2018 Nov 06;10(4):null
pubmed: 30404188
Antimicrob Agents Chemother. 2007 Sep;51(9):3367-70
pubmed: 17576830
Mol Cell Neurosci. 2018 Jun;89:60-70
pubmed: 29635016
Neurosurg Focus. 2015 Mar;38(3):E9
pubmed: 25727231
J Immunol. 2017 Nov 1;199(9):3094-3105
pubmed: 28978693
Curr Pharm Des. 2016;22(9):1177-1193
pubmed: 26685681
Cell Death Dis. 2017 Jan 19;8(1):e2556
pubmed: 28102850
Bull World Health Organ. 2011 Oct 1;89(10):766-74, 774A-774E
pubmed: 22084515
Virol J. 2017 Jan 14;14(1):8
pubmed: 28088249
Glia. 2007 Apr 1;55(5):483-96
pubmed: 17203475
BMC Infect Dis. 2016 Feb 04;16:67
pubmed: 26847071
Rev Med Virol. 2016 Mar;26(2):129-41
pubmed: 26695690
J Infect Dis. 2015 Sep 1;212(5):715-25
pubmed: 25601942
N Engl J Med. 2017 Apr 13;376(15):1483-1485
pubmed: 28402771
Stem Cell Res Ther. 2017 Feb 16;8(1):38
pubmed: 28209182
Sci Rep. 2017 Aug 18;7(1):8789
pubmed: 28821775
Sci Transl Med. 2012 Nov 21;4(161):161ra150
pubmed: 23175708
Front Immunol. 2018 May 30;9:1148
pubmed: 29910805
J Virol. 2015 Dec 09;90(5):2676-89
pubmed: 26656690
Nat Commun. 2019 Feb 11;10(1):706
pubmed: 30742008
J Gen Virol. 2014 Jan;95(Pt 1):71-9
pubmed: 24114795
Nat Commun. 2017 Apr 26;8(1):14
pubmed: 28446752
Mol Neurobiol. 2017 Mar;54(2):1541-1551
pubmed: 26860411
J Immunol. 2015 Sep 1;195(5):2251-62
pubmed: 26202983
J Neurochem. 2008 Jun;105(5):1582-95
pubmed: 18208541
J Virol. 2016 Jan 27;90(7):3722-34
pubmed: 26819305
J Neuroinflammation. 2012 Jan 18;9:12
pubmed: 22251375
Sci Rep. 2015 Dec 02;5:17548
pubmed: 26626303
PLoS Pathog. 2015 Mar 27;11(3):e1004750
pubmed: 25816318
Mater Sci Eng C Mater Biol Appl. 2017 Jul 1;76:1316-1327
pubmed: 28482500
J Immunol. 2009 Aug 15;183(4):2462-74
pubmed: 19635909
Immunobiology. 2013 Oct;218(10):1235-47
pubmed: 23706498
Expert Opin Ther Targets. 2015;19(10):1379-95
pubmed: 26156208
Sci Rep. 2016 Sep 26;6:33698
pubmed: 27667714
J Virol. 2011 Jun;85(11):5446-55
pubmed: 21450826
J Neuroinflammation. 2012 Dec 17;9:270
pubmed: 23244217