Genital Involvement in Bullous Fixed Drug Eruption.
Adolescent
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents
/ adverse effects
Anti-Inflammatory Agents, Non-Steroidal
/ adverse effects
Blister
/ chemically induced
Child
Child, Preschool
Drug Eruptions
/ etiology
Female
Genital Diseases, Female
/ chemically induced
Genital Diseases, Male
/ chemically induced
Humans
Male
Middle Aged
Mucous Membrane
Retrospective Studies
Young Adult
Journal
Skinmed
ISSN: 1751-7125
Titre abrégé: Skinmed
Pays: United States
ID NLM: 101168327
Informations de publication
Date de publication:
2019
2019
Historique:
entrez:
30
11
2019
pubmed:
30
11
2019
medline:
6
5
2020
Statut:
epublish
Résumé
Bullous fixed drug eruption (FDE) is a severe reaction due to drug intake and requires specific management in dermatology. The sites of predilection are the lips, trunk, genitalia, and perineal area. The aim of our study was to assess the features and outcomes of bullous FDE with genital involvement through a retrospective study of 18 years (2000-2017) conducted in the Dermatology Department of Habib Thameur Hospital. Ten patients were included in the study. The ratio of men to women was 6.4. The mean age of the patients was 46.3 years. The most frequently affected genital site in men was the glans penis. Nonsteroidal anti-inflammatory drugs were the most frequent drugs associated with genital bullous FDE, followed by paracetamol and trimethoprim-sulfamethoxazole. Residual hyperpigmentation of the genitals was not observed in our patients. Genital involvement in bullous FDE is more frequent in men.
Substances chimiques
Anti-Bacterial Agents
0
Anti-Inflammatory Agents, Non-Steroidal
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM