Childhood trauma and coping in patients with psychotic disorders and obsessive-compulsive symptoms and in un-affected siblings.


Journal

Child abuse & neglect
ISSN: 1873-7757
Titre abrégé: Child Abuse Negl
Pays: England
ID NLM: 7801702

Informations de publication

Date de publication:
01 2020
Historique:
received: 15 04 2019
revised: 18 09 2019
accepted: 17 10 2019
pubmed: 30 11 2019
medline: 15 12 2020
entrez: 30 11 2019
Statut: ppublish

Résumé

Research on environmental and individual risk-factors in patients with a psychotic disorder and co-occurring obsessive-compulsive symptoms (OCS) is limited. This study aimed to examine the role of childhood trauma and coping on the occurrence of OCS in patients with a psychotic disorder and on a subclinical level in siblings. 626 patients and 638 siblings from the Genetic Risk and Outcome of Psychosis (GROUP) study were included in the current study. Differences between patients and siblings with and without OCS were analyzed with between-group comparisons. Mediation analyses investigated the effect of coping on the association between trauma and OCS severity. Patients and siblings with OCS reported more childhood traumatic events, particularly sexual (OR = 1.62 / 3.26) and emotional (OR = 1.47 / 2.04) abuse compared to those without OCS. Both patients (d = 0.69) and siblings (d = 0.49) with co-occurring OCS showed a higher tendency for dysfunctional passive coping strategies compared to the group without OCS. The tendency for passive coping mediated the association between sexual and emotional abuse and OCS severity in patients. Results imply that childhood trauma is associated with the presence of co-occurring OCS. Enhancing active coping strategies might have a beneficial effect in the prevention and treatment of co-occurring OCS in patients with psychotic disorders.

Sections du résumé

BACKGROUND
Research on environmental and individual risk-factors in patients with a psychotic disorder and co-occurring obsessive-compulsive symptoms (OCS) is limited.
OBJECTIVE
This study aimed to examine the role of childhood trauma and coping on the occurrence of OCS in patients with a psychotic disorder and on a subclinical level in siblings.
PARTICIPANTS AND SETTING
626 patients and 638 siblings from the Genetic Risk and Outcome of Psychosis (GROUP) study were included in the current study.
METHODS
Differences between patients and siblings with and without OCS were analyzed with between-group comparisons. Mediation analyses investigated the effect of coping on the association between trauma and OCS severity.
RESULTS
Patients and siblings with OCS reported more childhood traumatic events, particularly sexual (OR = 1.62 / 3.26) and emotional (OR = 1.47 / 2.04) abuse compared to those without OCS. Both patients (d = 0.69) and siblings (d = 0.49) with co-occurring OCS showed a higher tendency for dysfunctional passive coping strategies compared to the group without OCS. The tendency for passive coping mediated the association between sexual and emotional abuse and OCS severity in patients.
CONCLUSIONS
Results imply that childhood trauma is associated with the presence of co-occurring OCS. Enhancing active coping strategies might have a beneficial effect in the prevention and treatment of co-occurring OCS in patients with psychotic disorders.

Identifiants

pubmed: 31783309
pii: S0145-2134(19)30420-X
doi: 10.1016/j.chiabu.2019.104243
pii:
doi:

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

104243

Investigateurs

Behrooz Z Alizadeh (BZ)
Therese van Amelsvoort (T)
Agna A Bartels-Velthuis (AA)
Nico J van Beveren (NJ)
Richard Bruggeman (R)
Wiepke Cahn (W)
Lieuwe de Haan (L)
Philippe Delespaul (P)
Jurjen J Luykx (JJ)
Inez Myin-Germeys (I)
Rene S Kahn (RS)
Frederike Schirmbeck (F)
Claudia J P Simons (CJP)
Jim van Os (J)
Ruud van Winkel (R)

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Tristan C Renkema (TC)

Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands.

Lieuwe de Haan (L)

Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands; Arkin Institute for Mental Health, Klaprozenweg 111, 1033 NN, Amsterdam, the Netherlands.

Frederike Schirmbeck (F)

Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands; Arkin Institute for Mental Health, Klaprozenweg 111, 1033 NN, Amsterdam, the Netherlands. Electronic address: n.f.schirmbeck@amc.uva.nl.

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