Factors associated with healthy aging in septuagenarian and nonagenarian Mexican adults.
Aged
Aged, 80 and over
Aging
Alcohol Drinking
/ epidemiology
Chronic Disease
Depression
/ epidemiology
Exercise
Female
Follow-Up Studies
Health Status
Healthy Aging
Humans
Life Expectancy
Life Style
Longevity
Male
Mexico
/ epidemiology
Middle Aged
Obesity
/ epidemiology
Overweight
/ epidemiology
Proportional Hazards Models
Prospective Studies
Risk Factors
Sex Factors
Smoking
Thinness
/ epidemiology
Healthy aging
Longevity
Maternal longevity
Obesity
Older adults
Physical activity
Journal
Maturitas
ISSN: 1873-4111
Titre abrégé: Maturitas
Pays: Ireland
ID NLM: 7807333
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
27
05
2019
revised:
31
08
2019
accepted:
12
10
2019
entrez:
3
12
2019
pubmed:
4
12
2019
medline:
18
3
2020
Statut:
ppublish
Résumé
To examine the factors associated with healthy aging in a cohort of Mexican adults after a follow-up of 14 years. Participants were part of a prospective cohort of the Mexican Healthy Aging Study (MHAS), from which we included 5142 individuals aged 63 years or more. Healthy aging, defined as reaching age 77 or 90 without major chronic conditions or physical limitations. Information on age, education, marital status, smoking, alcohol consumption, physical activity, self-perceived depression, health conditions and history of age-related diseases was collected at baseline and follow-up. Among the overall cohort, 57.8% experienced healthy survival to age 77 and 42.2% had died before age 77 or were undergoing normal aging. Participants with long-lived parents and who exercised had a lower risk of being non-healthy agers. Being overweight, obese or a smoker increased the risk of being a non-healthy ager. Physically active participants had increased odds of healthy aging at age 77 (OR: 1.17; 95% CI: 1.01-1.46) and at age 90 (OR: 1.5; 95% CI: 1.01-2.24). Depression had a negative relationship with healthy aging at age 90 (OR: 0.66; 95% CI: 0.45- 0.97). Maternal longevity was associated with healthy aging only at age 77 (OR = 1.34; 95% CI: 1.04-1.72). Our findings support the view that a combination of genetic and behavioral factors is associated with healthy aging. In accordance with findings in Caucasian populations, our data suggest for the first time that there might also be a genetic determinant for healthy ageing in Latin Americans.
Identifiants
pubmed: 31787143
pii: S0378-5122(19)30541-9
doi: 10.1016/j.maturitas.2019.10.008
pmc: PMC7034719
mid: NIHMS1556672
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
21-27Subventions
Organisme : NIA NIH HHS
ID : R01 AG018016
Pays : United States
Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.
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