Long-term outcome of children born from mothers with autoimmune diseases.
Autoimmune diseases
Children's outcome
Neurodevelopmental outcome
Journal
Best practice & research. Clinical obstetrics & gynaecology
ISSN: 1532-1932
Titre abrégé: Best Pract Res Clin Obstet Gynaecol
Pays: Netherlands
ID NLM: 101121582
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
14
09
2019
revised:
28
10
2019
accepted:
04
11
2019
pubmed:
4
12
2019
medline:
17
6
2020
entrez:
3
12
2019
Statut:
ppublish
Résumé
Autoimmune diseases often affect young women and this may represent a problem in family planning. Pregnancies in these patients may carry several complications but nowadays the continued amelioration in treatment and management has greatly improved the pregnancy outcome. The main concern of these women obviously is the short- and long-term outcome of their children. A child born from a woman with autoimmune disease is potentially exposed in utero to maternal autoantibodies, cytokines, and drugs, and each item could impair his or her development. In addition, the maternal genetic heritage can favor autoimmunity. All these items could have a role, for example, in the development of autoimmune diseases (the same as the mother or different ones) or neurological disorders. Data in literature are controversial. This review will gather the available data possibly providing a useful tool for counseling future mothers.
Identifiants
pubmed: 31787531
pii: S1521-6934(19)30166-X
doi: 10.1016/j.bpobgyn.2019.11.003
pii:
doi:
Substances chimiques
Cytokines
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
107-116Informations de copyright
Copyright © 2019. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors have no conflicts of interest.