K
Adult
Arterioles
/ physiology
Humans
KATP Channels
/ metabolism
Male
Nitric Oxide Synthase
/ metabolism
Potassium Channels, Calcium-Activated
/ metabolism
Potassium Channels, Voltage-Gated
/ metabolism
Prostaglandin-Endoperoxide Synthases
/ metabolism
Regional Blood Flow
Skin
/ blood supply
Veins
/ physiology
Dermatology
Endothelium
Heat loss responses
Hyperpolarization
Ligand-gated ion channels
Journal
European journal of pharmacology
ISSN: 1879-0712
Titre abrégé: Eur J Pharmacol
Pays: Netherlands
ID NLM: 1254354
Informations de publication
Date de publication:
05 Jan 2020
05 Jan 2020
Historique:
received:
05
05
2019
revised:
23
11
2019
accepted:
29
11
2019
pubmed:
4
12
2019
medline:
3
6
2020
entrez:
3
12
2019
Statut:
ppublish
Résumé
The venoarteriolar reflex is a local mechanism that induces vasoconstriction during venous congestion in various tissues, including skin. This response is thought to play a critical role in minimizing capillary damage or edema resulting from overperfusion, though factors that modulate this response remain largely unknown. Here, we hypothesized that nitric oxide synthase (NOS), cyclooxygenase (COX), and Ca
Identifiants
pubmed: 31790651
pii: S0014-2999(19)30780-0
doi: 10.1016/j.ejphar.2019.172828
pii:
doi:
Substances chimiques
KATP Channels
0
Potassium Channels, Calcium-Activated
0
Potassium Channels, Voltage-Gated
0
Nitric Oxide Synthase
EC 1.14.13.39
Prostaglandin-Endoperoxide Synthases
EC 1.14.99.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
172828Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.