Pulmonary vein encirclement using an Ablation Index-guided point-by-point workflow: cardiovascular magnetic resonance assessment of left atrial scar formation.
Ablation Index
Atrial ablation scar
Cardiac magnetic resonance imaging
Point-by-point ablation
Pulmonary vein isolation
Journal
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
ISSN: 1532-2092
Titre abrégé: Europace
Pays: England
ID NLM: 100883649
Informations de publication
Date de publication:
01 Dec 2019
01 Dec 2019
Historique:
received:
18
04
2019
accepted:
24
07
2019
entrez:
4
12
2019
pubmed:
4
12
2019
medline:
3
10
2020
Statut:
ppublish
Résumé
A point-by-point workflow for pulmonary vein isolation (PVI) targeting pre-defined Ablation Index values (a composite of contact force, time, and power) and minimizing interlesion distance may optimize the creation of contiguous ablation lesions whilst minimizing scar formation. We aimed to compare ablation scar formation in patients undergoing PVI using this workflow to patients undergoing a continuous catheter drag workflow. Post-ablation cardiovascular magnetic resonance imaging was performed in patients undergoing 1st-time PVI using a parameter-guided point-by-point workflow (n = 26). Total left atrial scar burden and the width and continuity of the pulmonary vein encirclement were determined on analysis of atrial late gadolinium enhancement sequences. Comparison was made with a cohort of patients (n = 20) undergoing PVI using continuous drag lesions. Mean post-ablation scar burden and scar width were significantly lower in the point-by-point group than in the control group (6.6 ± 6.8% vs. 9.6 ± 5.0%, P = 0.03 and 7.9 ± 3.6 mm vs. 10.7 ± 2.3 mm, P = 0.003). More complete bilateral pulmonary vein encirclements were seen in the point-by-point group (P = 0.038). All patients achieved acute PVI. Pulmonary vein isolation using a point-by-point workflow is feasible and results in a lower scar burden and scar width with more complete pulmonary vein encirclements than a conventional drag lesion approach.
Identifiants
pubmed: 31793653
pii: 5561464
doi: 10.1093/europace/euz226
pmc: PMC6887923
mid: EMS84626
doi:
Substances chimiques
Contrast Media
0
Organometallic Compounds
0
gadobutrol
1BJ477IO2L
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1817-1823Subventions
Organisme : British Heart Foundation
ID : FS/18/27/33543
Pays : United Kingdom
Organisme : British Heart Foundation
ID : PG/13/37/30280
Pays : United Kingdom
Informations de copyright
© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.
Références
J Cardiovasc Electrophysiol. 2014 Jul;25(7):701-8
pubmed: 24575734
J Am Coll Cardiol. 2011 Oct 4;58(15):1614-21
pubmed: 21958889
Eur Heart J. 2014 Jun 7;35(22):1486-95
pubmed: 24419806
Circ Arrhythm Electrophysiol. 2015 Apr;8(2):270-8
pubmed: 25593109
Heart Rhythm. 2008 May;5(5):656-62
pubmed: 18452866
JACC Clin Electrophysiol. 2018 Jan;4(1):99-108
pubmed: 29600792
JACC Clin Electrophysiol. 2015 Oct;1(5):421-431
pubmed: 29759471
Circ Arrhythm Electrophysiol. 2013 Apr;6(2):327-33
pubmed: 23515263
Europace. 2017 May 1;19(5):775-783
pubmed: 27247002
Europace. 2018 Nov 1;20(FI_3):f419-f427
pubmed: 29315411
Gastroenterol Hepatol (N Y). 2012 Jun;8(6):414-6
pubmed: 22933882
Europace. 2018 Dec 1;20(12):2028-2035
pubmed: 29701778
J Am Coll Cardiol. 2008 Oct 7;52(15):1263-71
pubmed: 18926331
J Am Coll Cardiol. 2012 Mar 6;59(10):930-8
pubmed: 22381429
Circulation. 2005 Aug 2;112(5):627-35
pubmed: 16061753
J Cardiovasc Magn Reson. 2018 Mar 19;20(1):21
pubmed: 29554919
JACC Cardiovasc Imaging. 2009 Mar;2(3):308-16
pubmed: 19356576
J Interv Card Electrophysiol. 2013 Nov;38(2):123-9
pubmed: 24022756
Heart Rhythm. 2012 Dec;9(12):2003-9
pubmed: 23000671
Circ Arrhythm Electrophysiol. 2017 Apr;10(4):null
pubmed: 28381417
JACC Cardiovasc Imaging. 2014 Jul;7(7):653-63
pubmed: 24813966