First description of parasite load and clinicopathological and anatomopathological changes in a dog naturally coinfected with Dioctophyme renale and Leishmania infantum in Brazil.
Dioctophymatosis
Dogs
Pathology
Visceral leishmaniasis
Journal
Veterinary parasitology, regional studies and reports
ISSN: 2405-9390
Titre abrégé: Vet Parasitol Reg Stud Reports
Pays: Netherlands
ID NLM: 101680410
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
06
08
2019
revised:
08
10
2019
accepted:
11
11
2019
entrez:
5
12
2019
pubmed:
5
12
2019
medline:
17
6
2020
Statut:
ppublish
Résumé
This article reports the case of a domestic dog naturally coinfected with the nematode Dioctophyme renale and with the protozoan Leishmania infantum. The dog exhibited no clinical signs but had normocytic hypochromic anemia, hyperproteinemia, hyperglobulinemia, hypoalbuminemia, and hematuria. Necropsy revealed eight D. renale specimens in the abdominal cavity and in right kidney whose parenchyma was atrophied. Histopathological analysis showed glomerular atrophy, fibrosis and a marked diffuse pyogranulomatous inflammatory infiltrate in the right kidney. Moderate multifocal granulomatous peritonitis was observed in the greater omentum. Several Dioctophyme renale eggs were present amidst the inflammatory infiltrate of the right kidney and greater omentum. Leishmania infantum parasites were detected in perirenal adipose tissue of the right kidney, greater omentum, spleen, bone marrow, and popliteal lymph node. The high D. renale load and the severe and uncommon histological alterations associated with the eggs of this parasite may have been influenced by coinfection with L. infantum.
Identifiants
pubmed: 31796167
pii: S2405-9390(19)30207-2
doi: 10.1016/j.vprsr.2019.100351
pii:
doi:
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
100351Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.