Acute retinal necrosis by herpes simplex virus type 1: an unusual presentation of a primary infection.
Acyclovir
/ administration & dosage
Administration, Intravenous
Antiviral Agents
/ administration & dosage
Eye Infections, Viral
/ complications
Herpesvirus 1, Human
/ isolation & purification
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Retinal Detachment
/ etiology
Retinal Necrosis Syndrome, Acute
/ complications
Vitreous Body
/ virology
cranial nerves
infectious diseases
neuroopthalmology
retina
visual pathway
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
02 Dec 2019
02 Dec 2019
Historique:
entrez:
5
12
2019
pubmed:
5
12
2019
medline:
25
4
2020
Statut:
epublish
Résumé
Herpes simplex virus (HSV) can affect the central nervous system causing meningitis, encephalitis and, rarely, acute retinal necrosis. We present a case of a 46-year-old man, previously healthy complaining of a 5-day persistent headache and sudden loss of vision of his left eye that progressed to the right. We started ceftriaxone, methylprednisolone and acyclovir for suspected encephalitis with vasculitis. HSV-1 was identified in vitreous and aqueous humour. Therapy with acyclovir was maintained and two intravitreous boluses of foscarnet were administered, without improvement. Usually being a benign infection, HSV can, in rare cases like this, have catastrophic effects in the optic tract.
Identifiants
pubmed: 31796440
pii: 12/12/e232566
doi: 10.1136/bcr-2019-232566
pmc: PMC7001697
pii:
doi:
Substances chimiques
Antiviral Agents
0
Acyclovir
X4HES1O11F
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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