Changes in typical beliefs in response to complicated grief treatment.
assessment/diagnosis
cognition
grief/bereavement/complicated grief
suicide/self harm
treatment
Journal
Depression and anxiety
ISSN: 1520-6394
Titre abrégé: Depress Anxiety
Pays: United States
ID NLM: 9708816
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
23
04
2019
revised:
09
11
2019
accepted:
28
11
2019
pubmed:
6
12
2019
medline:
6
6
2020
entrez:
6
12
2019
Statut:
ppublish
Résumé
Prolonged grief disorder (PGD) is a new diagnosis in the 11th edition of the International Classification of Diseases, estimated to affect 1 in 10 bereaved people and causing significant distress and impairment. Maladaptive thoughts play an important role in PGD. We have previously validated the typical beliefs questionnaire (TBQ), which contains five kinds of thinking commonly seen in PGD: protesting the death, negative thoughts about the world, needing the person, less grief is wrong, and grieving too much. The current paper examines the role of maladaptive cognition as measured by the TBQ in PGD and its change with treatment. Among participants in a multisite clinical trial including 394 adults, we examined (a) the relationship between maladaptive thoughts at baseline and treatment outcomes, (b) the relationship between maladaptive thoughts and suicidality at baseline and posttreatment, and (c) the effect of treatment with and without complicated grief therapy (CGT) on maladaptive thinking. TBQ scores were associated with treatment outcomes and were strongly related to suicidal thinking before and after treatment. TBQ scores showed significantly greater reduction in participants who received CGT with citalopram versus citalopram alone (adjusted mean standard error [SE] difference, -2.45 [0.85]; p = .004) and those who received CGT with placebo versus placebo alone (adjusted mean [SE] difference, -3.44 [0.90]; p < .001). Maladaptive thoughts, as measured by the TBQ, have clinical and research significance for PGD and its treatment.
Sections du résumé
BACKGROUND
Prolonged grief disorder (PGD) is a new diagnosis in the 11th edition of the International Classification of Diseases, estimated to affect 1 in 10 bereaved people and causing significant distress and impairment. Maladaptive thoughts play an important role in PGD. We have previously validated the typical beliefs questionnaire (TBQ), which contains five kinds of thinking commonly seen in PGD: protesting the death, negative thoughts about the world, needing the person, less grief is wrong, and grieving too much. The current paper examines the role of maladaptive cognition as measured by the TBQ in PGD and its change with treatment.
METHODS
Among participants in a multisite clinical trial including 394 adults, we examined (a) the relationship between maladaptive thoughts at baseline and treatment outcomes, (b) the relationship between maladaptive thoughts and suicidality at baseline and posttreatment, and (c) the effect of treatment with and without complicated grief therapy (CGT) on maladaptive thinking.
RESULTS
TBQ scores were associated with treatment outcomes and were strongly related to suicidal thinking before and after treatment. TBQ scores showed significantly greater reduction in participants who received CGT with citalopram versus citalopram alone (adjusted mean standard error [SE] difference, -2.45 [0.85]; p = .004) and those who received CGT with placebo versus placebo alone (adjusted mean [SE] difference, -3.44 [0.90]; p < .001).
CONCLUSIONS
Maladaptive thoughts, as measured by the TBQ, have clinical and research significance for PGD and its treatment.
Identifiants
pubmed: 31804005
doi: 10.1002/da.22981
pmc: PMC6952544
mid: NIHMS1062457
doi:
Substances chimiques
Citalopram
0DHU5B8D6V
Types de publication
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
81-89Subventions
Organisme : NIMH NIH HHS
ID : R01 MH060783
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH085297
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH085308
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH085288
Pays : United States
Informations de copyright
© 2019 Wiley Periodicals, Inc.
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