Screening of chiral shift reagents suitable to generically separate the enantiomers of V-agents by
(31)P NMR spectroscopy
Absolute configuration
Chiral LC-MS and LC-MS/MS
Chiral solvating agents (CSA)
Semi-preparative separation
Three-fold coordination
V-agents
Journal
Toxicology letters
ISSN: 1879-3169
Titre abrégé: Toxicol Lett
Pays: Netherlands
ID NLM: 7709027
Informations de publication
Date de publication:
01 Mar 2020
01 Mar 2020
Historique:
received:
24
07
2019
revised:
28
11
2019
accepted:
01
12
2019
pubmed:
6
12
2019
medline:
14
1
2020
entrez:
6
12
2019
Statut:
ppublish
Résumé
Fourteen amino acids protected at the N-terminal and at their side chains were screened for resolving the enantiomers of V-agents by NMR. While none of the shift reagents tested showed really effective separation in proton NMR, two of them (BOC-Gln(Xan)-OH, 16, and Z-Arg(Z)
Identifiants
pubmed: 31805340
pii: S0378-4274(19)30389-3
doi: 10.1016/j.toxlet.2019.12.004
pii:
doi:
Substances chimiques
Amino Acids
0
Organophosphorus Compounds
0
Solvents
0
Phosphorus
27YLU75U4W
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
28-36Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.