Analysis of the Molecular Signaling Signatures of Muscle Protein Wasting Between the Intercostal Muscles and the Gastrocnemius Muscles in


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
01 Dec 2019
Historique:
received: 18 10 2019
revised: 22 11 2019
accepted: 28 11 2019
entrez: 7 12 2019
pubmed: 7 12 2019
medline: 9 4 2020
Statut: epublish

Résumé

Type 2 diabetes (T2D) patients suffer from dyspnea, which contributes to disease-related morbidity. Although T2D has been reported to induce a catabolic state in skeletal muscle, whether T2D induces muscle wasting in respiratory muscles has not yet been investigated. In this study, we examine the difference in the molecular signaling signature of muscle wasting between the intercostal and gastrocnemius muscles using

Identifiants

pubmed: 31805681
pii: ijms20236062
doi: 10.3390/ijms20236062
pmc: PMC6929000
pii:
doi:

Substances chimiques

Muscle Proteins 0
Mechanistic Target of Rapamycin Complex 1 EC 2.7.11.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Ministry of Science and ICT
ID : 2018R1A2B6004513
Organisme : the ministry of education
ID : 2017R1C1B5016952
Organisme : Korea Health Industry Development Institute
ID : HI17C0426
Pays : Republic of Korea
Organisme : Gil Medical Center, Gachon University
ID : FRD2018-5189

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Auteurs

Kun Woo Kim (KW)

Department of Thoracic and Cardiovascular Surgery, Gachon University Gil Medical Center, College of Medicine, Gachon University, Incheon 21565, Korea.

Mi-Ock Baek (MO)

Department of Molecular Medicine, School of Medicine, Gachon University, Incheon 21999, Korea.
Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21936, Korea.
Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Korea.

Ji-Young Choi (JY)

Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21936, Korea.

Kuk Hui Son (KH)

Department of Thoracic and Cardiovascular Surgery, Gachon University Gil Medical Center, College of Medicine, Gachon University, Incheon 21565, Korea.

Mee-Sup Yoon (MS)

Department of Molecular Medicine, School of Medicine, Gachon University, Incheon 21999, Korea.
Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21936, Korea.
Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Korea.

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Classifications MeSH