Atypical anti-glomerular basement membrane disease presenting as macroscopic haematuria, loin pain and acute kidney injury after intensive exercise.

acute kidney injury atypical anti-glomerular basement membrane disease exercise haematuria loin pain

Journal

Clinical kidney journal
ISSN: 2048-8505
Titre abrégé: Clin Kidney J
Pays: England
ID NLM: 101579321

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 03 12 2018
entrez: 7 12 2019
pubmed: 7 12 2019
medline: 7 12 2019
Statut: epublish

Résumé

We report a 35-year-old man who suffered from recurrent macroscopic haematuria after intensive exercise. One episode was associated with bilateral loin (flank) pain and severe acute kidney injury. His kidney biopsy revealed an atypical anti-glomerular basement membrane (GBM) disease typified by bright linear GBM staining for monotypic immunoglobulin G but without a diffuse crescentic phenotype and no circulating anti-GBM antibody. Outcome was spontaneously favourable. The patient had no recurrence or urine abnormality without running. The original presentation emphasized that exercise could reveal an underlying glomerulopathy.

Identifiants

pubmed: 31807293
doi: 10.1093/ckj/sfz044
pii: sfz044
pmc: PMC6885666
doi:

Types de publication

Journal Article

Langues

eng

Pagination

801-802

Informations de copyright

© The Author(s) 2019. Published by Oxford University Press on behalf of ERA-EDTA.

Références

Kidney Int. 2016 Apr;89(4):897-908
pubmed: 26994577
Am J Kidney Dis. 2006 Mar;47(3):419-27
pubmed: 16490620
Clin J Am Soc Nephrol. 2012 Jan;7(1):175-84
pubmed: 22096039
Ren Fail. 2014 Jun;36(5):701-3
pubmed: 24865509
Nephrol Dial Transplant. 2004 Jun;19(6):1447-53
pubmed: 15150354

Auteurs

Arnaud Le Flecher (A)

Department of Nephrology - Transplantation, CHU de la Réunion Felix Guyon, Saint Denis, Réunion, France.

Nicolas Viallet (N)

Department of Nephrology - Transplantation, CHU de la Réunion Felix Guyon, Saint Denis, Réunion, France.

Delphine Hebmann (D)

Department of Nephrology - Transplantation, CHU de la Réunion Felix Guyon, Saint Denis, Réunion, France.

Bertrand Chauveau (B)

Department of Pathology, CHU Necker-Enfants Malades, Paris, France.

Henri Vacher Coponat (H)

Department of Nephrology - Transplantation, CHU de la Réunion Felix Guyon, Saint Denis, Réunion, France.
Université de la Réunion, UFR Santé, Réunion, France.

Classifications MeSH