Artificial colloids versus human albumin for the treatment of ovarian hyperstimulation syndrome: A retrospective cohort study.
Colloid
Length of stay.
Treatment
Ovarian hyperstimulation syndrome
Journal
International journal of reproductive biomedicine
ISSN: 2476-4108
Titre abrégé: Int J Reprod Biomed
Pays: Iran
ID NLM: 101679102
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
14
01
2019
revised:
17
03
2019
accepted:
12
06
2019
entrez:
7
12
2019
pubmed:
7
12
2019
medline:
7
12
2019
Statut:
epublish
Résumé
The optimal colloid solution for the treatment of ovarian hyperstimulation syndrome (OHSS) remains to be established. We aimed to compare artificial colloids (AC) with human albumin (HA) for the treatment of OHSS. In this retrospective cohort study, data for OHSS participants were collected from a national inpatient database in Japan. The participants received intravenous fluid management with AC (n = 156) or HA (n = 127). We compared the two groups in terms of the length of stay, development of post-treatment complications, and termination surgery. In multivariable linear regression analyses for log-transformed length of stay with reference to the OHSS participants receiving AC, the regression coefficient (95% confidence interval) in participants receiving HA was 0.03 (-0.04-0.09, p = 0.42). Thromboembolism occurred in two participants in the HA group and three participants in the AC group. Two participants in the HA group suffered renal failure during hospitalization. No participants underwent termination surgery in the two groups. The present results showed comparable efficacy between AC and HA for the treatment of OHSS. There were no significant differences in post-treatment complications between the two groups.
Sections du résumé
BACKGROUND
BACKGROUND
The optimal colloid solution for the treatment of ovarian hyperstimulation syndrome (OHSS) remains to be established.
OBJECTIVE
OBJECTIVE
We aimed to compare artificial colloids (AC) with human albumin (HA) for the treatment of OHSS.
MATERIALS AND METHODS
METHODS
In this retrospective cohort study, data for OHSS participants were collected from a national inpatient database in Japan. The participants received intravenous fluid management with AC (n = 156) or HA (n = 127). We compared the two groups in terms of the length of stay, development of post-treatment complications, and termination surgery.
RESULTS
RESULTS
In multivariable linear regression analyses for log-transformed length of stay with reference to the OHSS participants receiving AC, the regression coefficient (95% confidence interval) in participants receiving HA was 0.03 (-0.04-0.09, p = 0.42). Thromboembolism occurred in two participants in the HA group and three participants in the AC group. Two participants in the HA group suffered renal failure during hospitalization. No participants underwent termination surgery in the two groups.
CONCLUSION
CONCLUSIONS
The present results showed comparable efficacy between AC and HA for the treatment of OHSS. There were no significant differences in post-treatment complications between the two groups.
Identifiants
pubmed: 31807719
doi: 10.18502/ijrm.v17i10.5287
pmc: PMC6844285
doi:
Types de publication
Journal Article
Langues
eng
Pagination
709-716Informations de copyright
Copyright © 2019 Tetsuji Minami et al.
Déclaration de conflit d'intérêts
No conflicts of interest are disclosed.
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