A self-assembling amphiphilic dendrimer nanotracer for SPECT imaging.
Adenocarcinoma
/ diagnostic imaging
Animals
Cell Line, Tumor
Chelating Agents
/ chemical synthesis
Dendrimers
/ chemical synthesis
Heterocyclic Compounds, 1-Ring
/ chemical synthesis
Humans
Indium
Indium Radioisotopes
Mice
Micelles
Nanostructures
/ chemistry
Pancreatic Neoplasms
/ diagnostic imaging
Radioisotopes
Surface-Active Agents
/ chemical synthesis
Tomography, Emission-Computed, Single-Photon
/ methods
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
19 Dec 2019
19 Dec 2019
Historique:
pubmed:
7
12
2019
medline:
29
1
2020
entrez:
7
12
2019
Statut:
ppublish
Résumé
Bioimaging has revolutionized modern medicine, and nanotechnology can offer further specific and sensitive imaging. We report here an amphiphilic dendrimer able to self-assemble into supramolecular nanomicelles for effective tumor detection using SPECT radioimaging. This highlights the promising potential of supramolecular dendrimer platforms for biomedical imaging.
Substances chimiques
Chelating Agents
0
Dendrimers
0
Heterocyclic Compounds, 1-Ring
0
Indium Radioisotopes
0
Indium-115
0
Micelles
0
Radioisotopes
0
Surface-Active Agents
0
Indium
045A6V3VFX
1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
1HTE449DGZ
Indium-111
E9NGC49E0T
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM