Postpartum Readmissions Among Women With Diabetes.
Adolescent
Adult
Age Distribution
Databases, Factual
Diabetes Mellitus, Type 1
/ epidemiology
Diabetes Mellitus, Type 2
/ epidemiology
Diabetes, Gestational
/ epidemiology
Female
Humans
Linear Models
Middle Aged
Patient Readmission
/ statistics & numerical data
Postpartum Period
Pregnancy
Pregnancy in Diabetics
/ epidemiology
Retrospective Studies
Risk Factors
Time Factors
United States
/ epidemiology
Young Adult
Journal
Obstetrics and gynecology
ISSN: 1873-233X
Titre abrégé: Obstet Gynecol
Pays: United States
ID NLM: 0401101
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
pubmed:
7
12
2019
medline:
16
4
2020
entrez:
7
12
2019
Statut:
ppublish
Résumé
To estimate whether women with diabetes are at risk for 60-day postpartum readmissions and associated complications. The Nationwide Readmissions Database from 2010 to 2014 was analyzed to determine risk for 60-day postpartum readmissions among women with type 1 diabetes mellitus (DM), type 2 DM, gestational diabetes mellitus (GDM), and unspecified DM compared with women with no diabetes. Secondary outcomes included evaluating risk for overall severe maternal morbidity during readmissions, as well as wound complications, acute diabetic complications such as diabetic ketoacidosis, venous thromboembolism, and hypertensive diseases of pregnancy. Billing data were used to ascertain both exposures and outcomes. Adjusted log-linear regression models including demographic, hospital, medical and obstetric, and hospital factors were performed with adjusted risk ratios (aRRs) and with 95% Cis as measures of association. Of an estimated 15.7 million delivery hospitalizations, 1.1 million occurred among women with diabetes, of whom 3.2% had type 1 DM, 9.1% type 2 DM, 86.6% GDM, and 1.1% unspecified diabetes. Compared with women without diabetes (1.5% risk for readmission), risk for readmission was significantly higher for women with type 1 DM (4.4%), unspecified diabetes (4.0%), type 2 DM (3.9%), and GDM (2.0%) (P<.01). After adjusting for hospital, demographic, medical, and obstetric risk factors, type 1 DM (aRR 1.77, 95% CI 1.69-1.87), type 2 DM (aRR 1.46, 95% CI 1.42-1.51), unspecified (aRR 1.73, 95% CI 1.59-1.89) and gestational diabetes (aRR 1.16, 95% CI 1.14-1.17) retained increased risk. Among women with diabetes public insurance, lower ZIP code income quartiles, and hospitals with high safety net burdens were associated with higher risk for readmission. In both unadjusted and adjusted analyses, all diabetes diagnoses were associated with readmissions for wound complications, hypertensive diseases of pregnancy, and severe maternal morbidity. Although overall risk for readmission is low, pregnancies complicated by pregestational diabetes in particular are at increased risk. Women in this high-risk group should receive coordinated care and be monitored closely in the postpartum period.
Identifiants
pubmed: 31809421
doi: 10.1097/AOG.0000000000003551
pmc: PMC6923572
mid: NIHMS1539512
pii: 00006250-202001000-00012
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
80-89Subventions
Organisme : NICHD NIH HHS
ID : K08 HD082287
Pays : United States
Références
Diabet Med. 2015 Oct;32(10):1361-7
pubmed: 25865087
World Neurosurg. 2018 Nov;119:e284-e293
pubmed: 30055361
Diabet Med. 2001 Jul;18(7):573-7
pubmed: 11553188
J Clin Transl Endocrinol. 2017 Apr 08;8:29-34
pubmed: 29067256
Matern Child Health J. 2008 Jul;12(4):469-77
pubmed: 17690963
J Clin Med Res. 2017 Jan;9(1):35-39
pubmed: 27924173
Am J Obstet Gynecol. 2016 Jul;215(1):113.e1-113.e10
pubmed: 27829570
N Engl J Med. 2009 Apr 2;360(14):1418-28
pubmed: 19339721
BMJ Open Diabetes Res Care. 2019 Apr 8;7(1):e000621
pubmed: 31114699
Am J Obstet Gynecol. 2009 Apr;200(4):365.e1-8
pubmed: 18691691
Diabetes Care. 1996 Oct;19(10):1067-74
pubmed: 8886551
Am J Manag Care. 2010 Oct;16(10):760-7
pubmed: 20964472
Intern Med J. 2005 May;35(5):296-9
pubmed: 15845113
JAMA Surg. 2016 Feb;151(2):120-8
pubmed: 26466334
Am J Obstet Gynecol. 2018 Oct;219(4):401.e1-401.e14
pubmed: 30017675
Obstet Gynecol. 2018 Sep;132(3):784-785
pubmed: 30134408
Diabetol Metab Syndr. 2012 Sep 11;4(1):41
pubmed: 22964143
Diabetes Care. 2010 Apr;33(4):768-73
pubmed: 20067968
Obstet Gynecol. 2019 Apr;133(4):712-719
pubmed: 30870276