Myxoid Liposarcoma With Skeletal Metastases: Pathophysiology and Imaging Characteristics.
Journal
Current problems in diagnostic radiology
ISSN: 1535-6302
Titre abrégé: Curr Probl Diagn Radiol
Pays: United States
ID NLM: 7607123
Informations de publication
Date de publication:
Historique:
received:
24
07
2019
revised:
17
10
2019
accepted:
23
10
2019
pubmed:
10
12
2019
medline:
16
10
2021
entrez:
10
12
2019
Statut:
ppublish
Résumé
Liposarcoma is a commonly occurring soft tissue sarcoma that can be divided into 4 subtypes. Myxoid and round cell liposarcoma (MRCL) represent one of these subtypes and are classified together due to their shared chromosomal translocation. Histologic analysis of MRCL reveals a myxoid matrix with a delicate capillary network and dispersed lipoblasts. Varying degrees of round cell component are also observed, with greater amounts of round cells indicating a higher histologic grade and poorer prognosis. MRCL has a unique pattern of spread due to its initial tendency to spread to extrapulmonary sites. Additionally, skeletal metastases are frequently found in cases of MRCL. While various imaging techniques are used to visualize MRCL and metastases, magnetic resonance imaging is generally the preferred method. This article reviews the pathophysiology and imaging features of MRCL as well as the imaging characteristics, advantages, and drawbacks of multiple imaging modalities for visualizing bone metastases.
Identifiants
pubmed: 31813645
pii: S0363-0188(19)30221-X
doi: 10.1067/j.cpradiol.2019.10.008
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
66-73Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.