Precursors to Cholangiocarcinoma.
Journal
Gastroenterology research and practice
ISSN: 1687-6121
Titre abrégé: Gastroenterol Res Pract
Pays: Egypt
ID NLM: 101475557
Informations de publication
Date de publication:
2019
2019
Historique:
received:
04
06
2019
accepted:
18
09
2019
entrez:
10
12
2019
pubmed:
10
12
2019
medline:
10
12
2019
Statut:
epublish
Résumé
Cancers of the biliary tract include intra- and extrahepatic cholangiocarcinomas and gallbladder cancer. Biliary tract cancers are diseases with unfavorable prognoses. In recent years, several lesions have been described as precursors that precede biliary cancers. They include flat and microscopic lesions known as biliary intraepithelial neoplasia, macroscopic and tumor-forming intraductal papillary biliary neoplasia, intraductal tubular neoplasia, and mucinous cystic neoplasm of the bile duct. These conditions are rarely diagnosed, while their natural history and progression to cancer have yet to be adequately characterized. This review examines the epidemiology, pathology, molecular biology, diagnosis, and therapy of these various precursors. Further research is required if we are to better understand this evolving field and improve the prevention and early detection of bile duct cancer.
Identifiants
pubmed: 31814823
doi: 10.1155/2019/1389289
pmc: PMC6877954
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1389289Informations de copyright
Copyright © 2019 Tomas Hucl.
Déclaration de conflit d'intérêts
There is no conflict of interest regarding the publication of this paper.
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