Mechanisms of Disease Progression and Resistance to Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukemia: An Update.

Blast Crisis / drug therapy Disease Progression Drug Resistance, Neoplasm Fusion Proteins, bcr-abl / antagonists & inhibitors Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy Neoplastic Stem Cells / enzymology Protein Kinase Inhibitors / therapeutic use
BCR-ABL1 blastic phase chronic myeloid leukemia persistence resistance tyrosine kinase inhibitors

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
05 Dec 2019
Historique:
received: 05 11 2019
revised: 29 11 2019
accepted: 04 12 2019
entrez: 11 12 2019
pubmed: 11 12 2019
medline: 16 4 2020
Statut: epublish

Résumé

Chronic myeloid leukemia (CML) is characterized by the presence of the

Identifiants

DOI: 10.3390/ijms20246141 PMID: 31817512 PMC: PMC6940932
pubmed: 31817512
pii: ijms20246141
doi: 10.3390/ijms20246141
pmc: PMC6940932
pii:
doi:

Substances chimiques

BCR-ABL1 fusion protein, human 0
Protein Kinase Inhibitors 0
Fusion Proteins, bcr-abl EC 2.7.10.2

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Références

Nature. 2010 Aug 5;466(7307):765-8
pubmed: 20639863
Cell Stem Cell. 2008 Aug 7;3(2):207-20
pubmed: 18682242
Mol Cancer. 2018 Feb 19;17(1):49
pubmed: 29455643
Blood. 2006 Mar 15;107(6):2507-16
pubmed: 16293596
Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17468-73
pubmed: 21987825
Ann Hematol. 2000 Aug;79(8):424-31
pubmed: 10985361
Blood. 2016 Jun 2;127(22):2742-50
pubmed: 27006386
Blood. 2008 Jan 15;111(2):816-28
pubmed: 17925491
Blood. 1988 Jul;72(1):294-8
pubmed: 3164637
J Clin Oncol. 2018 Jan 20;36(3):231-237
pubmed: 29091516
Clin Cancer Res. 2006 Dec 15;12(24):7374-9
pubmed: 17189410
Blood. 2013 Jan 17;121(3):489-98
pubmed: 23223358
Leukemia. 2017 Oct;31(10):2065-2074
pubmed: 28321124
Blood. 2000 Feb 15;95(4):1144-50
pubmed: 10666183
Mutat Res. 2001 Sep 1;480-481:37-50
pubmed: 11506797
Cancer Cell. 2014 Sep 8;26(3):428-442
pubmed: 25132497
Acta Biochim Pol. 2017;64(1):1-10
pubmed: 27904889
Blood. 2004 Dec 1;104(12):3746-53
pubmed: 15304390
Blood Adv. 2017 Jul 31;1(18):1369-1381
pubmed: 29296778
Leukemia. 1996 Jul;10(7):1134-8
pubmed: 8683992
Leuk Lymphoma. 1993;11 Suppl 1:11-5
pubmed: 8251885
Nature. 2010 Feb 4;463(7281):676-80
pubmed: 20130650
J Clin Invest. 2007 Sep;117(9):2562-9
pubmed: 17710227
Drug Discov Today. 2019 Jul;24(7):1355-1369
pubmed: 31102734
Mol Cancer. 2011 Apr 18;10:41
pubmed: 21501493
Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17967-72
pubmed: 19004799
J Clin Oncol. 2003 Apr 15;21(8):1472-9
pubmed: 12697869
Blood. 2003 Jun 15;101(12):4701-7
pubmed: 12576334
Nature. 2008 May 1;453(7191):110-4
pubmed: 18408710
Stem Cells. 2014 Sep;32(9):2324-37
pubmed: 24806995
Clin Cancer Res. 2007 Sep 1;13(17):5048-55
pubmed: 17785556
Blood. 2013 Oct 24;122(17):3034-44
pubmed: 23970380
Cancer Genet Cytogenet. 1983 May;9(1):81-91
pubmed: 6573228
J Transl Med. 2015 Feb 12;13:52
pubmed: 25889244
Leuk Lymphoma. 2000 Aug;38(5-6):587-97
pubmed: 10953980
Cancer Cell. 2008 Sep 9;14(3):238-49
pubmed: 18772113
Leuk Res. 2009 Mar;33(3):418-25
pubmed: 18760473
Cancer Discov. 2016 Nov;6(11):1248-1257
pubmed: 27630125
Blood. 2007 May 1;109(9):4016-9
pubmed: 17213283
EMBO J. 1998 Aug 3;17(15):4442-55
pubmed: 9687511
Leukemia. 2009 May;23(5):892-9
pubmed: 19158832
Cell Stem Cell. 2016 Aug 4;19(2):177-191
pubmed: 27292188
Nature. 2017 May 25;545(7655):500-504
pubmed: 28514443
Haematologica. 2018 Dec;103(12):2016-2025
pubmed: 30049824
Nat Med. 2006 Oct;12(10):1175-80
pubmed: 16998483
Am J Hematol. 2018 Jan;93(1):84-90
pubmed: 29027261
J Clin Invest. 2011 Jan;121(1):396-409
pubmed: 21157039
Blood. 2015 Mar 12;125(11):1772-81
pubmed: 25573989
Leukemia. 2016 Jul;30(7):1493-501
pubmed: 27044711
Cancer Res. 1997 May 1;57(9):1678-81
pubmed: 9135007
Cancer Cell. 2003 Feb;3(2):145-60
pubmed: 12620409
Cancer Cell. 2012 Apr 17;21(4):577-92
pubmed: 22516264
Sci Transl Med. 2014 Sep 3;6(252):252ra121
pubmed: 25186176
Leukemia. 2014 Aug;28(8):1745-7
pubmed: 24618732
Blood. 2003 Jun 1;101(11):4583-8
pubmed: 12576338
J Clin Oncol. 1999 Dec;17(12):3753-66
pubmed: 10577847
Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6293-7
pubmed: 2068108
Cancer Res. 2011 Feb 1;71(3):842-51
pubmed: 21123451
Leukemia. 2011 Jan;25(1):178-81
pubmed: 20962862
N Engl J Med. 1999 Jul 15;341(3):164-72
pubmed: 10403855
Blood. 2012 Mar 22;119(12):2873-82
pubmed: 22318203
Gene. 2019 Feb 20;686:85-91
pubmed: 30399426
Blood. 2006 May 15;107(10):4080-9
pubmed: 16418324
Blood. 2010 Apr 8;115(14):2872-81
pubmed: 19861684
Blood. 1995 Sep 15;86(6):2371-8
pubmed: 7662984
Cancer. 2017 Nov 15;123(22):4391-4402
pubmed: 28743165
Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):1041-6
pubmed: 23275297
Leukemia. 2016 Sep;30(9):1861-8
pubmed: 27211271
Blood. 2014 Feb 27;123(9):1361-71
pubmed: 24394666
Exp Hematol. 2015 Sep;43(9):775-80
pubmed: 26118501
Proc Natl Acad Sci U S A. 1989 Sep;86(17):6783-7
pubmed: 2771957
Blood. 2006 Jul 1;108(1):319-27
pubmed: 16527898
Haematologica. 2003 Mar;88(3):260-7
pubmed: 12651263
Int J Hematol. 2011 Apr;93(4):465-473
pubmed: 21387093
Am J Clin Pathol. 1997 Feb;107(2):168-76
pubmed: 9024065
Blood. 1994 Jun 15;83(12):3449-56
pubmed: 8204873
Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2794-9
pubmed: 16477019
Science. 1992 Oct 30;258(5083):808-12
pubmed: 1439790
Blood. 2012 Jul 26;120(4):761-7
pubmed: 22692507
Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):4004-8
pubmed: 8171026
Blood. 2011 Sep 29;118(13):3657-60
pubmed: 21791426
Leuk Res. 2008 Apr;32(4):673-4
pubmed: 17889935
Front Oncol. 2018 May 30;8:194
pubmed: 29900128
Haematologica. 2010 Sep;95(9):1604-7
pubmed: 20435623
J Clin Invest. 2013 Oct;123(10):4144-57
pubmed: 23999433
Cell. 2010 Mar 5;140(5):652-65
pubmed: 20211135
Blood. 2017 Mar 23;129(12):1595-1606
pubmed: 28159740
Blood. 2007 Aug 1;110(3):994-1003
pubmed: 17475908
Genes Chromosomes Cancer. 2007 Nov;46(11):1039-50
pubmed: 17696194
Mol Cell Biol. 1998 Jul;18(7):4301-14
pubmed: 9632814
Blood. 2017 Jan 12;129(2):199-208
pubmed: 27793879
Blood. 2008 Apr 1;111(7):3821-9
pubmed: 18235045
Cell Cycle. 2014;13(23):3727-41
pubmed: 25483082
Br J Haematol. 2014 May;165(3):414-6
pubmed: 24401018
PLoS One. 2011;6(7):e22110
pubmed: 21760961
Oncogene. 2018 May;37(21):2837-2849
pubmed: 29511345
Oncogene. 2013 Jan 31;32(5):589-98
pubmed: 22410779
N Engl J Med. 2004 Aug 12;351(7):657-67
pubmed: 15306667
Blood. 2008 Nov 1;112(9):3847-55
pubmed: 18650450
Hematol Oncol Clin North Am. 2017 Aug;31(4):589-612
pubmed: 28673390
Clin Epigenetics. 2019 Feb 11;11(1):25
pubmed: 30744689
Nat Med. 2010 Aug;16(8):903-8
pubmed: 20616797
Leukemia. 2005 Oct;19(10):1774-82
pubmed: 16136169
Blood. 2010 Feb 4;115(5):1049-53
pubmed: 19965645
Blood. 1990 Dec 15;76(12):2594-8
pubmed: 2265251
Blood. 2013 Aug 8;122(6):872-84
pubmed: 23803709
Leukemia. 2011 Mar;25(3):557-60
pubmed: 21274004
Blood. 2009 Aug 20;114(8):1528-36
pubmed: 19420358
Nature. 2003 May 22;423(6938):409-14
pubmed: 12717450
Blood. 2008 Apr 1;111(7):3735-41
pubmed: 18202228
Nature. 2009 Apr 9;458(7239):776-9
pubmed: 19169242
Blood. 2018 Aug 30;132(9):948-961
pubmed: 29967129
Ann Hematol. 2011 Nov;90(11):1255-64
pubmed: 21384125
Blood. 1995 Apr 15;85(8):2013-6
pubmed: 7718873
Biochem J. 2001 Feb 1;353(Pt 3):417-39
pubmed: 11171037
Cancer Res. 1996 Mar 1;56(5):973-77
pubmed: 8640788
Acta Haematol. 2007;117(4):236-7
pubmed: 17308370
Turk J Haematol. 2015 Jun;32(2):193-4
pubmed: 26316496
Leuk Res. 2012 Apr;36(4):418-21
pubmed: 22309891
Genes Cancer. 2016 May;7(5-6):201-208
pubmed: 27551334
Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13137-42
pubmed: 8917557
Cancer Genet Cytogenet. 1993 Nov;71(1):87-93
pubmed: 8275458
Nat Genet. 2002 Jan;30(1):48-58
pubmed: 11753385
Exp Hematol. 2003 Mar;31(3):204-10
pubmed: 12644017
Cancer. 2017 May 15;123(10):1791-1799
pubmed: 28026860
J Immunol. 1996 Jan 15;156(2):585-92
pubmed: 8543809
Leukemia. 2015 Mar;29(3):586-597
pubmed: 25134459
Cancer Cell. 2007 Dec;12(6):528-41
pubmed: 18068630
J Clin Invest. 1993 Oct;92(4):1925-39
pubmed: 8408645
J Clin Invest. 2009 May;119(5):1109-23
pubmed: 19363292
Cancer Cell. 2005 Nov;8(5):355-68
pubmed: 16286244
Blood. 2000 May 1;95(9):2990-2
pubmed: 10779450
J Clin Oncol. 2010 Aug 20;28(24):3890-8
pubmed: 20660833
Genes Chromosomes Cancer. 2006 May;45(5):482-94
pubmed: 16425296
Blood. 2011 Jun 16;117(24):6660-8
pubmed: 21490338
Int J Cancer. 1976 Jul 15;18(1):24-30
pubmed: 1065618
Blood. 2008 Aug 15;112(4):1413-23
pubmed: 18524993
Blood. 2011 Dec 22;118(26):6760-8
pubmed: 22039253
Blood. 1991 Dec 15;78(12):3259-68
pubmed: 1683797
Blood. 2012 Feb 9;119(6):1501-10
pubmed: 22184410
Blood. 2011 May 26;117(21):e198-206
pubmed: 21346257
Blood. 2011 Sep 29;118(13):3634-44
pubmed: 21821701
Leukemia. 2013 Mar;27(3):629-34
pubmed: 23047475
Annu Rev Med. 2009;60:167-79
pubmed: 19630570
Br J Haematol. 1995 Nov;91(3):625-9
pubmed: 8555065
BMC Genomics. 2010 Jan 18;11:41
pubmed: 20082691
J Biol Chem. 2000 Aug 11;275(32):24273-8
pubmed: 10833515
Leukemia. 2016 May;30(5):1044-54
pubmed: 26837842
Oncotarget. 2016 Jun 7;7(23):35293-301
pubmed: 27167108
Trends Mol Med. 2006 Dec;12(12):580-7
pubmed: 17071139
Blood. 2006 Jul 1;108(1):28-37
pubmed: 16522812
Blood. 2003 May 15;101(10):3794-800
pubmed: 12560227
Leukemia. 2003 Feb;17(2):461-3
pubmed: 12592348
Cell Death Differ. 2005 Jun;12(6):534-40
pubmed: 15846378
Leukemia. 2006 Oct;20(10):1767-73
pubmed: 16855631
Haematologica. 2019 Sep;104(9):1789-1797
pubmed: 30819912
Cell Death Differ. 2015 Feb;22(2):187-98
pubmed: 24992931
Blood. 2011 Nov 17;118(20):5565-72
pubmed: 21931114
J Clin Oncol. 2016 Jul 10;34(20):2333-40
pubmed: 27217448
Blood. 2002 Jan 1;99(1):319-25
pubmed: 11756187
Cold Spring Harb Symp Quant Biol. 2008;73:461-7
pubmed: 19028987
N Engl J Med. 2003 Oct 9;349(15):1423-32
pubmed: 14534335
Proc Natl Acad Sci U S A. 2006 May 9;103(19):7444-9
pubmed: 16651519
Cancer. 1987 Sep 1;60(5):974-9
pubmed: 3475159
BMC Cancer. 2015 Dec 16;15:970
pubmed: 26674644
Br J Haematol. 2014 Jul;166(2):250-3
pubmed: 24673583
Blood. 1985 Dec;66(6):1326-35
pubmed: 3864497
Blood. 1991 Jun 1;77(11):2431-4
pubmed: 2039823
Cancer Genet Cytogenet. 1985 Sep;18(1):65-79
pubmed: 3861236
Trends Cell Biol. 2014 Jul;24(7):400-6
pubmed: 24698685
Blood. 1995 Jul 1;86(1):1-14
pubmed: 7795214
Blood. 2007 Jun 15;109(12):5411-21
pubmed: 17347407
Cancer Res. 2003 Sep 15;63(18):5716-22
pubmed: 14522890
J Biol Chem. 2018 Jul 6;293(27):10512-10523
pubmed: 29247009
Blood. 2012 Jan 12;119(2):530-9
pubmed: 22101898

Auteurs

Luana Bavaro (L)

Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology "L. e A. Seràgnoli", University of Bologna, 40138 Bologna, Italy.

Margherita Martelli (M)

Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology "L. e A. Seràgnoli", University of Bologna, 40138 Bologna, Italy.

Michele Cavo (M)

Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology "L. e A. Seràgnoli", University of Bologna, 40138 Bologna, Italy.

Simona Soverini (S)

Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology "L. e A. Seràgnoli", University of Bologna, 40138 Bologna, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Carcinogenèse › Transformation cellulaire néoplasique › Crise blastique › Mechanisms of Disease Progression and...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Évolution de la maladie › Mechanisms of Disease Progression and...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Résistance aux médicaments antinéoplasiques › Mechanisms of Disease Progression and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines tumorales › Protéines oncogènes › Protéines proto-oncogènes › Protéines proto-oncogènes c-bcr › Protéines de fusion bcr-abl › Mechanisms of Disease Progression and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Mechanisms of Disease Progression and...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Leucémie myéloïde chronique BCR-ABL positive › Mechanisms of Disease Progression and...
questionsmedicales.fr › Cellules › Cellules souches › Cellules souches tumorales › Mechanisms of Disease Progression and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de protéines kinases › Mechanisms of Disease Progression and...