Animal Models of Chronic Cerebral Hypoperfusion: From Mouse to Primate.
chronic cerebral hypoperfusion
mouse model of asymmetric carotid artery surgery
mouse model of bilateral common carotid artery stenosis
non-human primate model of 3-vessel occlusion
rat model of bilateral carotid artery occlusion
vascular cognitive impairment
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
07 Dec 2019
07 Dec 2019
Historique:
received:
02
10
2019
revised:
17
11
2019
accepted:
03
12
2019
entrez:
11
12
2019
pubmed:
11
12
2019
medline:
2
5
2020
Statut:
epublish
Résumé
Vascular cognitive impairment (VCI) or vascular dementia occurs as a result of brain ischemia and represents the second most common type of dementia after Alzheimer's disease. To explore the underlying mechanisms of VCI, several animal models of chronic cerebral hypoperfusion have been developed in rats, mice, and primates. We established a mouse model of chronic cerebral hypoperfusion by narrowing the bilateral common carotid arteries with microcoils, eventually resulting in hippocampal atrophy. In addition, a mouse model of white matter infarct-related damage with cognitive and motor dysfunction has also been established by asymmetric common carotid artery surgery. Although most experiments studying chronic cerebral hypoperfusion have been performed in rodents because of the ease of handling and greater ethical acceptability, non-human primates appear to represent the best model for the study of VCI, due to their similarities in much larger white matter volume and amyloid β depositions like humans. Therefore, we also recently developed a baboon model of VCI through three-vessel occlusion (both the internal carotid arteries and the left vertebral artery). In this review, several animal models of chronic cerebral hypoperfusion, from mouse to primate, are extensively discussed to aid in better understanding of pathophysiology of VCI.
Identifiants
pubmed: 31817864
pii: ijms20246176
doi: 10.3390/ijms20246176
pmc: PMC6941004
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Grant-in-Aid for Scientific Research on Priority Areas from the Japanese Ministry of Education, Science and Culture
ID : 19K21321
Références
Stroke. 2010 Dec;41(12):2938-43
pubmed: 20947840
Acta Neuropathol. 2003 Dec;106(6):527-34
pubmed: 13680276
Am J Med. 2018 Dec;131(12):1408-1417
pubmed: 30076825
Sci Rep. 2017 Jun 27;7(1):4299
pubmed: 28655874
J Cereb Blood Flow Metab. 2006 Feb;26(2):253-62
pubmed: 16079792
J Neuroinflammation. 2017 Apr 11;14(1):81
pubmed: 28399892
Stroke. 2011 Sep;42(9):2672-713
pubmed: 21778438
J Neurol Sci. 2012 Nov 15;322(1-2):107-11
pubmed: 22925533
Stroke. 1995 Dec;26(12):2338-46
pubmed: 7491661
Stroke. 2004 Nov;35(11):2598-603
pubmed: 15472111
Lancet. 2015 Oct 24;386(10004):1698-706
pubmed: 26595643
Neuropharmacology. 2018 May 15;134(Pt B):226-239
pubmed: 29273521
J Neurochem. 2010 Nov;115(4):814-28
pubmed: 20731763
Sci Rep. 2019 Feb 26;9(1):2827
pubmed: 30808940
J Cereb Blood Flow Metab. 2013 May;33(5):760-3
pubmed: 23403376
Cell Mol Neurobiol. 2016 Mar;36(2):233-9
pubmed: 26988696
Brain Res Rev. 2007 Apr;54(1):162-80
pubmed: 17296232
Stroke. 2004 Apr;35(4):942-7
pubmed: 15001785
Stem Cell Res. 2015 Jul;15(1):68-74
pubmed: 26002630
Stroke. 2014 Nov;45(11):3403-11
pubmed: 25213338
J Cereb Blood Flow Metab. 2019 Jan;39(1):44-57
pubmed: 29053032
Neurobiol Aging. 2012 Jan;33(1):205.e19-29
pubmed: 20961666
Brain Res Bull. 2011 Jan 15;84(1):69-74
pubmed: 21074599
Panminerva Med. 2004 Dec;46(4):217-26
pubmed: 15876978
PLoS One. 2011 Jan 27;6(1):e16567
pubmed: 21305033
Neuropathol Appl Neurobiol. 2012 Aug;38(5):487-99
pubmed: 22126319
Clin Sci (Lond). 2017 Sep 28;131(19):2451-2468
pubmed: 28963120
Stroke. 2007 Oct;38(10):2826-32
pubmed: 17761909
Biochim Biophys Acta. 2016 May;1862(5):860-8
pubmed: 26704177
Acta Neuropathol. 2001 Feb;101(2):145-53
pubmed: 11271369
Stroke. 2016 Jul;47(7):1953-9
pubmed: 27301939
Brain. 2016 Jan;139(Pt 1):242-58
pubmed: 26667280
J Cereb Blood Flow Metab. 2008 Dec;28(12):1877-91
pubmed: 18698331
Eur J Pharmacol. 1999 Jun 30;375(1-3):41-50
pubmed: 10443563
Exp Neurol. 2015 Oct;272:97-108
pubmed: 25987538
Acta Neuropathol. 2016 May;131(5):659-85
pubmed: 27062261
Stroke. 1999 Dec;30(12):2752-8
pubmed: 10583007
Neuroscience. 2001;108(2):237-47
pubmed: 11734357
Stroke. 2010 Aug;41(8):1798-806
pubmed: 20595663
Stroke. 2010 Jun;41(6):1278-84
pubmed: 20448204
Transl Stroke Res. 2016 Oct;7(5):407-14
pubmed: 27498679
JAMA Neurol. 2015 Nov;72(11):1288-94
pubmed: 26389654
Stroke. 2011 Apr;42(4):1122-8
pubmed: 21393586
J Neurosci. 2017 Mar 15;37(11):2870-2877
pubmed: 28188218
Hypertension. 2019 Jan;73(1):217-228
pubmed: 30571552
Neurobiol Aging. 2015 Jan;36(1):485-91
pubmed: 25444608
Neurobiol Dis. 2004 Jun;16(1):212-9
pubmed: 15207278
Aging Dis. 2018 Oct 1;9(5):869-879
pubmed: 30271664
Endocrinology. 2006 Apr;147(4):1642-53
pubmed: 16384868
Sci Rep. 2016 Aug 18;6:32179
pubmed: 27535801
Circulation. 2012 Jul 10;126(2):196-206
pubmed: 22668972
J Neurol Sci. 2012 Nov 15;322(1-2):2-10
pubmed: 22575403
Clin Sci Mol Med Suppl. 1975 Jun;2:161s-163s
pubmed: 1077766
J Alzheimers Dis. 2016 Mar 5;52(1):113-26
pubmed: 27060955
J Cereb Blood Flow Metab. 2013 Nov;33(11):1666-84
pubmed: 23963364
Sci Rep. 2016 Apr 06;6:23964
pubmed: 27050297
J Cereb Blood Flow Metab. 1998 May;18(5):570-9
pubmed: 9591849
J Vasc Surg. 2019 Nov 4;:null
pubmed: 31699511
Hypertension. 2012 Jul;60(1):188-97
pubmed: 22615109
Neuroophthalmology. 2014 Jun 9;38(4):180-188
pubmed: 27928297
J Neurol Neurosurg Psychiatry. 2009 Apr;80(4):366-70
pubmed: 18977814
Circulation. 2017 Aug 22;136(8):719-728
pubmed: 28588075
J Neurosci. 2015 Mar 4;35(9):3915-28
pubmed: 25740520
J Cereb Blood Flow Metab. 2006 Aug;26(8):1066-75
pubmed: 16395291
Brain Res. 2016 Sep 1;1646:494-503
pubmed: 27350079
Methods Mol Biol. 2014;1135:95-102
pubmed: 24510857
J Cereb Blood Flow Metab. 2018 Jan;38(1):151-165
pubmed: 28273725
Neurology. 2015 Mar 31;84(13):1294-300
pubmed: 25762710
Brain Res Mol Brain Res. 2005 Sep 13;139(1):169-77
pubmed: 15964096
Biochim Biophys Acta. 2016 May;1862(5):975-82
pubmed: 26704178
Eur J Heart Fail. 2017 Feb;19(2):253-260
pubmed: 27612177
J Neurol Sci. 2005 Mar 15;229-230:3-6
pubmed: 15760612