Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in

Enterococcus faecalis antibiotic resistance antimicrobial peptides cell membrane adaptation daptomycin

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
26 Dec 2019
Historique:
pubmed: 11 12 2019
medline: 11 12 2019
entrez: 11 12 2019
Statut: ppublish

Résumé

Bacteria have developed several evolutionary strategies to protect their cell membranes (CMs) from the attack of antibiotics and antimicrobial peptides (AMPs) produced by the innate immune system, including remodeling of phospholipid content and localization. Multidrug-resistant

Identifiants

DOI: 10.1073/pnas.1916037116 PMID: 31818937 PMC: PMC6936494
pubmed: 31818937
pii: 1916037116
doi: 10.1073/pnas.1916037116
pmc: PMC6936494
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

26925-26932

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI080714
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI110432
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI143229
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI134637
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE025015
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI055449
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI076406
Pays : United States
Organisme : NIAID NIH HHS
ID : K08 AI113317
Pays : United States
Organisme : NIAID NIH HHS
ID : K08 AI135093
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE017382
Pays : United States
Organisme : NIAID NIH HHS
ID : K24 AI121296
Pays : United States

Auteurs

Ayesha Khan (A)

Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
MD Anderson Cancer Center, University of Texas Health Graduate School of Biomedical Sciences, Houston, TX 77030.
ORCID: 0000-0002-0489-0712

Milya Davlieva (M)

Department of Biosciences, Rice University, Houston, TX 77005.

Diana Panesso (D)

Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, 110111 Bogotá, Colombia.

Sandra Rincon (S)

Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, 110111 Bogotá, Colombia.

William R Miller (WR)

Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.

Lorena Diaz (L)

Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, 110111 Bogotá, Colombia.
Millennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R), 8320000 Santiago, Chile.

Jinnethe Reyes (J)

Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, 110111 Bogotá, Colombia.

Melissa R Cruz (MR)

Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.

Orville Pemberton (O)

Department of Biosciences, Rice University, Houston, TX 77005.

April H Nguyen (AH)

Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
MD Anderson Cancer Center, University of Texas Health Graduate School of Biomedical Sciences, Houston, TX 77030.

Sara D Siegel (SD)

Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.

Paul J Planet (PJ)

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Pediatric Infectious Disease Division, Children's Hospital of Philadelphia, Philadelphia, PA.
Sackler Institute for Comparative Genomics, American Museum of Natural History, New York, NY 12560.

Apurva Narechania (A)

Sackler Institute for Comparative Genomics, American Museum of Natural History, New York, NY 12560.

Mauricio Latorre (M)

Center for Genome Regulation and Center for Mathematical Modeling, Universidad de Chile, 8320000 Santiago, Chile.
Laboratorio de Bioinformática y Expresión Génica, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, 8320000 Santiago, Chile.
Laboratorio de Biotecnología, Instituto de Ciencias de la Ingeniería, Universidad de O'Higgins, 2841158 Rancagua, Chile.

Rafael Rios (R)

Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, 110111 Bogotá, Colombia.

Kavindra V Singh (KV)

Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.

Hung Ton-That (H)

Division of Oral Biology and Medicine, School of Dentistry, University of California, Los Angeles, CA 90024.

Danielle A Garsin (DA)

Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
MD Anderson Cancer Center, University of Texas Health Graduate School of Biomedical Sciences, Houston, TX 77030.

Truc T Tran (TT)

Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.

Yousif Shamoo (Y)

Department of Biosciences, Rice University, Houston, TX 77005.

Cesar A Arias (CA)

Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030.
MD Anderson Cancer Center, University of Texas Health Graduate School of Biomedical Sciences, Houston, TX 77030.
Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, 110111 Bogotá, Colombia.
Center for Infectious Diseases, School of Public Health, University of Texas Health Science Center, Houston, TX 77030.

Classifications MeSH