Imidazoline Receptor System: The Past, the Present, and the Future.

Animals Antihypertensive Agents / pharmacology Clonidine / pharmacology Humans Imidazoles / pharmacology Imidazoline Receptors / metabolism Imidazolines / metabolism Ligands Quinazolines / pharmacology Randomized Controlled Trials as Topic

Journal

Pharmacological reviews
ISSN: 1521-0081
Titre abrégé: Pharmacol Rev
Pays: United States
ID NLM: 0421737

Informations de publication

Date de publication:
01 2020
Historique:
entrez: 11 12 2019
pubmed: 11 12 2019
medline: 20 9 2020
Statut: ppublish

Résumé

Imidazoline receptors historically referred to a family of nonadrenergic binding sites that recognize compounds with an imidazoline moiety, although this has proven to be an oversimplification. For example, none of the proposed endogenous ligands for imidazoline receptors contain an imidazoline moiety but they are diverse in their chemical structure. Three receptor subtypes (I

Identifiants

DOI: 10.1124/pr.118.016311 PMID: 31819014
pubmed: 31819014
pii: 72/1/50
doi: 10.1124/pr.118.016311
doi:

Substances chimiques

Antihypertensive Agents 0
CR4056 0
Imidazoles 0
Imidazoline Receptors 0
Imidazolines 0
Ligands 0
Quinazolines 0
Clonidine MN3L5RMN02

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

50-79

Informations de copyright

Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics.

Auteurs

Pascal Bousquet (P)

Faculty of Medicine, University of Strasbourg, Strasbourg, France (P.B.); Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada (A.H.); Laboratory of Neuropharmacology, University Research Institute on Health Sciences, University of the Balearic Islands, Palma de Malllorca, Spain (J.A.G.-S.); and Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York (J.-X.L.).

Alan Hudson (A)

Faculty of Medicine, University of Strasbourg, Strasbourg, France (P.B.); Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada (A.H.); Laboratory of Neuropharmacology, University Research Institute on Health Sciences, University of the Balearic Islands, Palma de Malllorca, Spain (J.A.G.-S.); and Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York (J.-X.L.).

Jesús A García-Sevilla (JA)

Faculty of Medicine, University of Strasbourg, Strasbourg, France (P.B.); Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada (A.H.); Laboratory of Neuropharmacology, University Research Institute on Health Sciences, University of the Balearic Islands, Palma de Malllorca, Spain (J.A.G.-S.); and Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York (J.-X.L.).

Jun-Xu Li (JX)

Faculty of Medicine, University of Strasbourg, Strasbourg, France (P.B.); Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada (A.H.); Laboratory of Neuropharmacology, University Research Institute on Health Sciences, University of the Balearic Islands, Palma de Malllorca, Spain (J.A.G.-S.); and Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York (J.-X.L.) junxuli@buffalo.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Imidazoline Receptor System: The Past, the...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents cardiovasculaires › Antihypertenseurs › Imidazoline Receptor System: The Past, the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Imidazoles › Imidazolines › Clonidine › Imidazoline Receptor System: The Past, the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Imidazoline Receptor System: The Past, the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Imidazoles › Imidazoline Receptor System: The Past, the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Récepteurs des médicaments › Récepteurs des imidazolines › Imidazoline Receptor System: The Past, the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Imidazoles › Imidazolines › Imidazoline Receptor System: The Past, the...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Imidazoline Receptor System: The Past, the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinazolines › Imidazoline Receptor System: The Past, the...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › Essais cliniques contrôlés comme sujet › Essais contrôlés randomisés comme sujet › Imidazoline Receptor System: The Past, the...