Binding and Reactivity of Copper to R
Journal
Inorganic chemistry
ISSN: 1520-510X
Titre abrégé: Inorg Chem
Pays: United States
ID NLM: 0366543
Informations de publication
Date de publication:
06 Jan 2020
06 Jan 2020
Historique:
pubmed:
11
12
2019
medline:
6
2
2020
entrez:
11
12
2019
Statut:
ppublish
Résumé
Tau protein is present in significant amounts in neurons, where it contributes to the stabilization of microtubules. Insoluble neurofibrillary tangles of tau are associated with several neurological disorders known as tauopathies, among which is Alzheimer's disease. In neurons, tau binds tubulin through its microtubule binding domain which comprises four imperfect repeats (R
Identifiants
pubmed: 31820933
doi: 10.1021/acs.inorgchem.9b02266
doi:
Substances chimiques
Coordination Complexes
0
Peptide Fragments
0
tau Proteins
0
Copper
789U1901C5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM