Clinical importance of preoperative and postoperative prognostic nutritional index in patients with pancreatic ductal adenocarcinoma.
Overall survival
Pancreatic ductal adenocarcinoma
Prognostic nutritional index
Journal
Annals of hepato-biliary-pancreatic surgery
ISSN: 2508-5859
Titre abrégé: Ann Hepatobiliary Pancreat Surg
Pays: Korea (South)
ID NLM: 101698342
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
11
07
2019
accepted:
11
07
2019
entrez:
12
12
2019
pubmed:
12
12
2019
medline:
12
12
2019
Statut:
ppublish
Résumé
The prognostic nutritional index (PNI) is based on the albumin concentration and absolute lymphocyte count and is designed to assess the nutritional and immunological status of patients. In this study, we evaluated the prognostic importance of the preoperative and postoperative PNI in patients who underwent curative resection of pancreatic ductal adenocarcinoma (PDAC). From 2006 to 2017, 50 patients with PDAC underwent curative resection at our hospital. We performed distal pancreatectomy (DP) with splenectomy in 15 patients, pancreaticoduodenectomy (PD) in 27 patients, PD combined with portal vein partial resection in 6 patients, and total pancreatectomy with splenectomy in 2 patients. We compared the preoperative PNI and postoperative PNI (1 and 2 months postoperatively) and analyzed the prognostic importance for these patients. The mean PNI significantly decreased from 45.5 preoperatively to 39.8 at 1 month postoperatively ( Effective postoperative nutrition may have a prognostic benefit for patients with operable PDAC.
Sections du résumé
BACKGROUNDS/AIMS
OBJECTIVE
The prognostic nutritional index (PNI) is based on the albumin concentration and absolute lymphocyte count and is designed to assess the nutritional and immunological status of patients. In this study, we evaluated the prognostic importance of the preoperative and postoperative PNI in patients who underwent curative resection of pancreatic ductal adenocarcinoma (PDAC).
METHODS
METHODS
From 2006 to 2017, 50 patients with PDAC underwent curative resection at our hospital. We performed distal pancreatectomy (DP) with splenectomy in 15 patients, pancreaticoduodenectomy (PD) in 27 patients, PD combined with portal vein partial resection in 6 patients, and total pancreatectomy with splenectomy in 2 patients. We compared the preoperative PNI and postoperative PNI (1 and 2 months postoperatively) and analyzed the prognostic importance for these patients.
RESULTS
RESULTS
The mean PNI significantly decreased from 45.5 preoperatively to 39.8 at 1 month postoperatively (
CONCLUSIONS
CONCLUSIONS
Effective postoperative nutrition may have a prognostic benefit for patients with operable PDAC.
Identifiants
pubmed: 31825004
doi: 10.14701/ahbps.2019.23.4.372
pmc: PMC6893056
doi:
Types de publication
Journal Article
Langues
eng
Pagination
372-376Informations de copyright
Copyright © 2019 by The Korean Association of Hepato-Biliary-Pancreatic Surgery.
Références
Int J Surg. 2018 Dec;60:67-73
pubmed: 30399450
Surg Today. 2012 Jun;42(6):532-5
pubmed: 22139087
J Thorac Dis. 2018 Sep;10(9):5298-5307
pubmed: 30416777
Surg Today. 2018 Apr;48(4):395-403
pubmed: 29027629
PLoS One. 2016 Mar 29;11(3):e0152523
pubmed: 27023252
Hepatobiliary Pancreat Dis Int. 2018 Jun;17(3):263-268
pubmed: 29752133
J Nippon Med Sch. 2018;85(4):208-214
pubmed: 30259889
Eur J Surg Oncol. 2019 Mar;45(3):425-431
pubmed: 30366877
Anesth Analg. 2010 Jun 1;110(6):1636-43
pubmed: 20435944
World J Gastroenterol. 2015 Jan 7;21(1):262-8
pubmed: 25574100
Nat Rev Clin Oncol. 2015 Apr;12(4):213-26
pubmed: 25601442
Hepatogastroenterology. 2015 Jun;62(140):859-62
pubmed: 26902016
Nihon Geka Gakkai Zasshi. 1984 Sep;85(9):1001-5
pubmed: 6438478
Int Anesthesiol Clin. 2016 Fall;54(4):58-71
pubmed: 27648891