Gellan gum-based delivery systems of therapeutic agents and cells.


Journal

Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156

Informations de publication

Date de publication:
01 Feb 2020
Historique:
received: 10 06 2019
revised: 16 09 2019
accepted: 02 10 2019
entrez: 13 12 2019
pubmed: 13 12 2019
medline: 21 4 2020
Statut: ppublish

Résumé

The purpose of this review is to make a summary of high quality research trends using gellan gum (GG) as a polymeric constituent for the design of innovative drug delivery systems and devices for biomedical applications, such as cell therapy and regenerative medicine. The use of gellan gum is described both in its native form and as chemically functionalized derivatives or physically mixed with natural or synthetic materials. Starting from a systematic study of recent research works, the main properties of the native polysaccharide have been highlighted and therefore some improvements have been focused thanks to the design of chemically functionalized derivatives and the use of composite materials.

Identifiants

pubmed: 31826518
pii: S0144-8617(19)31097-5
doi: 10.1016/j.carbpol.2019.115430
pii:
doi:

Substances chimiques

Polysaccharides, Bacterial 0
gellan gum 7593U09I4D

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

115430

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Fabio Salvatore Palumbo (FS)

Università degli Studi di Palermo, Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Via Archirafi 32, 90123 Palermo, Italy.

Salvatore Federico (S)

Università degli Studi di Palermo, Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Via Archirafi 32, 90123 Palermo, Italy.

Giovanna Pitarresi (G)

Università degli Studi di Palermo, Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Via Archirafi 32, 90123 Palermo, Italy. Electronic address: giovanna.pitarresi@unipa.it.

Calogero Fiorica (C)

Università degli Studi di Palermo, Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Via Archirafi 32, 90123 Palermo, Italy.

Gaetano Giammona (G)

Università degli Studi di Palermo, Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Via Archirafi 32, 90123 Palermo, Italy; Institute of Biophysics at Palermo, Italian National Research Council, Via Ugo La Malfa 153, 90146 Palermo, Italy.

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Classifications MeSH