The paternal and maternal genetic history of Vietnamese populations.
Journal
European journal of human genetics : EJHG
ISSN: 1476-5438
Titre abrégé: Eur J Hum Genet
Pays: England
ID NLM: 9302235
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
received:
13
06
2019
accepted:
17
11
2019
revised:
14
10
2019
pubmed:
13
12
2019
medline:
26
5
2021
entrez:
13
12
2019
Statut:
ppublish
Résumé
Vietnam exhibits great cultural and linguistic diversity, yet the genetic history of Vietnamese populations remains poorly understood. Previous studies focused mostly on the majority Kinh group, and thus the genetic diversity of the many other groups has not yet been investigated. Here we analyze complete mtDNA genome sequences and ~2.3 Mb sequences of the male-specific portion of the Y chromosome from the Kinh and 16 minority populations, encompassing all five language families present in Vietnam. We find highly variable levels of diversity within and between groups that do not correlate with either geography or language family. In particular, the Mang and Sila have undergone recent, independent bottlenecks, while the majority group, Kinh, exhibits low levels of differentiation with other groups. The two Austronesian-speaking groups, Giarai and Ede, show a potential impact of matrilocality on their patterns of variation. Overall, we find that isolation, coupled with limited contact involving some groups, has been the major factor influencing the genetic structure of Vietnamese populations, and that there is substantial genetic diversity that is not represented by the Kinh.
Identifiants
pubmed: 31827276
doi: 10.1038/s41431-019-0557-4
pii: 10.1038/s41431-019-0557-4
pmc: PMC7171127
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
636-645Subventions
Organisme : Université de Lyon (University of Lyon)
ID : ANR-10-LABX-0081
Pays : International
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : ANR-11-IDEX-0007
Pays : International
Organisme : Ministry of Science and Technology (Ministry of Science and Technology of the Socialist Republic of Vietnam)
ID : DTDL.CN-05/15
Pays : International
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