Two Functional


Journal

Dermatology research and practice
ISSN: 1687-6105
Titre abrégé: Dermatol Res Pract
Pays: Egypt
ID NLM: 101312803

Informations de publication

Date de publication:
2019
Historique:
received: 28 08 2019
accepted: 15 10 2019
entrez: 13 12 2019
pubmed: 13 12 2019
medline: 13 12 2019
Statut: epublish

Résumé

Keloid is defined as a benign proliferative scar that grows beyond the confines of the original insult to the skin, invading into adjacent normal tissue. The pathogenesis of keloid is complex, and many evidences suggest the influence of genetic factors, among them the polymorphisms of the To investigate the association of rs1042522 (c.215G>C, p.Arg72Pro) and rs17878362 (16-bp insertion/duplication in intron 3) variants, two most frequently analyzed The rs1042522 and rs17878362 polymorphisms were identified by sequencing genomic DNA extracted from peripheral blood leukocytes of 86 keloid patients and from cordial blood leukocytes of 100 newborn infants consisting control group. The rs1042522 and rs17878362 Our results suggest the lack of association of rs1042522 and rs17878362

Identifiants

pubmed: 31827503
doi: 10.1155/2019/6179063
pmc: PMC6881576
doi:

Types de publication

Journal Article

Langues

eng

Pagination

6179063

Informations de copyright

Copyright © 2019 Andrzej Dmytrzak et al.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest regarding the publication of this paper.

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Auteurs

Andrzej Dmytrzak (A)

Aesthetic Med Andrzej Dmytrzak Prywatne Centrum Chirurgii Plastycznej i Rekonstrukcyjnej, ul. Niedzialkowskiego 47, 71-403 Szczecin, Poland.

Agnieszka Boroń (A)

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, al. Powstancow Wlkp. 72, 70-111 Szczecin, Poland.

Beata Łoniewska (B)

Department of Neonatal Diseases, Pomeranian Medical University, ul. Powstancow Wlkp. 72, 70-111 Szczecin, Poland.

Klaudyna Lewandowska (K)

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, al. Powstancow Wlkp. 72, 70-111 Szczecin, Poland.

Iwona Gorący (I)

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, al. Powstancow Wlkp. 72, 70-111 Szczecin, Poland.

Mariusz Kaczmarczyk (M)

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, al. Powstancow Wlkp. 72, 70-111 Szczecin, Poland.

Andrzej Ciechanowicz (A)

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, al. Powstancow Wlkp. 72, 70-111 Szczecin, Poland.

Classifications MeSH