5
Animals
Antibodies
/ blood
Antioxidants
/ chemistry
Aryldialkylphosphatase
/ blood
Catalase
/ metabolism
Cholesterol
/ analogs & derivatives
Diet
Erythrocytes
/ cytology
Glutathione Peroxidase
/ metabolism
Glutathione Reductase
/ metabolism
Ketocholesterols
/ immunology
Male
Malondialdehyde
/ metabolism
Oxidative Stress
/ drug effects
Phytosterols
/ pharmacology
Rats
Rats, Wistar
Superoxide Dismutase
/ metabolism
Journal
Oxidative medicine and cellular longevity
ISSN: 1942-0994
Titre abrégé: Oxid Med Cell Longev
Pays: United States
ID NLM: 101479826
Informations de publication
Date de publication:
2019
2019
Historique:
received:
10
06
2019
accepted:
16
09
2019
entrez:
13
12
2019
pubmed:
13
12
2019
medline:
28
4
2020
Statut:
epublish
Résumé
Cholesterol oxidation products have an established proatherogenic and cytotoxic effect. An increased exposure to these substances may be associated with the development of atherosclerosis and cancers. Relatively little, though, is known about the effect of phytosterol oxidation products, although phytosterols are present in commonly available and industrial food products. Thus, the aim of the research was to assess the effect of 5 The animals were divided into 3 groups and exposed to nutritional sterols by receiving feed containing 5 During the experiment, the levels of lipid peroxidation products increased, such as CD and anti-7-ketocholesterol antibodies. At the same time, the plasma levels of FRAP and serum activity of PON1 decreased alongside the reduced activity of GPx, GR, and SOD in RBCs. There was no effect of the studied compounds on the plasma MDA levels or on the activity of CAT and GST in RBCs. Both 5
Identifiants
pubmed: 31827670
doi: 10.1155/2019/1983975
pmc: PMC6881747
doi:
Substances chimiques
5,6-epoxycholesterol
0
Antibodies
0
Antioxidants
0
Ketocholesterols
0
Phytosterols
0
Malondialdehyde
4Y8F71G49Q
Cholesterol
97C5T2UQ7J
Catalase
EC 1.11.1.6
Glutathione Peroxidase
EC 1.11.1.9
Superoxide Dismutase
EC 1.15.1.1
Glutathione Reductase
EC 1.8.1.7
Aryldialkylphosphatase
EC 3.1.8.1
7-ketocholesterol
O7676FE78M
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1983975Informations de copyright
Copyright © 2019 Tomasz Wielkoszyński et al.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest regarding the publication of this paper.
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