Focus on the cetirizine use in clinical practice: a reappraisal 30 years later.
Antihistamines
Cetirizine
Clinical practice
H1 receptors
Histamine
Journal
Multidisciplinary respiratory medicine
ISSN: 1828-695X
Titre abrégé: Multidiscip Respir Med
Pays: Italy
ID NLM: 101477642
Informations de publication
Date de publication:
2019
2019
Historique:
received:
10
10
2019
accepted:
15
11
2019
entrez:
13
12
2019
pubmed:
13
12
2019
medline:
13
12
2019
Statut:
epublish
Résumé
Antihistamines are currently one of the most commonly administered categories of drugs. They are used to treat symptoms that are secondary to histamine release, which is typical of certain allergic conditions, including rhinitis, conjunctivitis, asthma, urticaria, and anaphylaxis. Cetirizine belongs to the second-generation family, so, it is very selective for peripheral H1 receptors, is potent and quickly relieves symptoms, exerts additional anti-allergic/anti-inflammatory effects, and is usually well-tolerated. It has been marketed 30 years ago. In these years, a remarkable body of evidence has been built. The current review provides a practical update on the use of cetirizine in clinical practice.
Identifiants
pubmed: 31827796
doi: 10.1186/s40248-019-0203-6
pii: 203
pmc: PMC6898951
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
40Informations de copyright
© The Author(s). 2019.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare that they participated in an advisory board organized by Dompé Farmaceutici S.p.A. Italy concerning the role of antihistamines in clinical practice. AGC is an Associate Editor of Multidisciplinary Respiratory Medicine.
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