Liver abscess: diagnostic and management issues found in the low resource setting.
amoebic
liver abscess
low-middle income countries
pyogenic
resource limited settings
Journal
British medical bulletin
ISSN: 1471-8391
Titre abrégé: Br Med Bull
Pays: England
ID NLM: 0376542
Informations de publication
Date de publication:
11 12 2019
11 12 2019
Historique:
received:
12
04
2019
revised:
29
08
2019
accepted:
16
09
2019
pubmed:
15
12
2019
medline:
6
6
2020
entrez:
15
12
2019
Statut:
ppublish
Résumé
Liver abscesses are mainly caused by parasitic or bacterial infection and are an important cause of hospitalization in low-middle income countries (LMIC). The pathophysiology of abscesses is different depending on the etiology and requires different strategies for diagnosis and management. This paper discusses pathophysiology and epidemiology, the current diagnostic approach and its limitations and management of liver abscess in low resource settings. We searched PubMed for relevant reviews by typing the following keywords: 'amoebic liver abscess' and 'pyogenic liver abscess'. Amoebic liver abscess can be treated medically while pyogenic liver abscess usually needs to be percutaneously drained and treated with effective antibiotics. In an LMIC setting, where misuse of antibiotics is a recognized issue, liver abscesses are a therapeutic conundrum, leaving little choices for treatment for physicians in low capacity settings. As antimicrobial resistance awareness and antibiotic stewardship programs are put into place, liver abscess management will likely improve in LMICs provided that systematic adapted guidelines are established and practiced. The lack of a quick and reliable diagnostic strategy in the majority of LMIC makes selection of appropriate treatment challenging.
Identifiants
pubmed: 31836890
pii: 5677141
doi: 10.1093/bmb/ldz032
pmc: PMC6992887
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
45-52Informations de copyright
© The Author(s) 2019. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
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