Organocatalytic Combinatorial Synthesis of Quinazoline, Quinoxaline and Bis(indolyl)methanes.
Organocatalyst
anticancer
green chemistry
heterocyclic
multicomponent
quinazoline.
Journal
Combinatorial chemistry & high throughput screening
ISSN: 1875-5402
Titre abrégé: Comb Chem High Throughput Screen
Pays: United Arab Emirates
ID NLM: 9810948
Informations de publication
Date de publication:
2020
2020
Historique:
received:
23
07
2019
revised:
24
11
2019
accepted:
29
11
2019
pubmed:
17
12
2019
medline:
1
4
2021
entrez:
17
12
2019
Statut:
ppublish
Résumé
An efficient and practical procedure for the synthesis of heterocyclic compounds such as quinazolines, quinoxalines and bis(indolyl)methanes was developed using 3,5-bis(trifluoromethyl) phenyl ammonium hexafluorophosphate (BFPHP) as a novel organocatalyst. All of the obtained products are known compounds and identified by IR, 1HNMR, 13CNMR and melting points. Various products were obtained in good to excellent yields under reaction conditions. The BFPHP organocatalyst demonstrates a novel class of non-asymmetric organocatalysts, which has gained much attention in green chemistry.
Identifiants
pubmed: 31838991
pii: CCHTS-EPUB-102976
doi: 10.2174/1386207323666191213123026
doi:
Substances chimiques
Indoles
0
Phosphoric Acids
0
Quinazolines
0
Quinoxalines
0
ammonium hexafluorophosphate
NS308031PJ
Methane
OP0UW79H66
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
83-88Informations de copyright
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