Patients undergoing interventions for claudication experience low perioperative morbidity but are at risk for worsening functional status and limb loss.
Aged
Amputation, Surgical
Blood Vessel Prosthesis Implantation
/ adverse effects
Databases, Factual
Dependent Ambulation
Disease Progression
Endovascular Procedures
/ adverse effects
Female
Health Status
Humans
Intermittent Claudication
/ diagnostic imaging
Limb Salvage
Male
Middle Aged
Mobility Limitation
New England
Peripheral Arterial Disease
/ diagnostic imaging
Progression-Free Survival
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
Claudication
Functional status
Lower extremity bypass
Peripheral vascular intervention
Vascular surgery
Journal
Journal of vascular surgery
ISSN: 1097-6809
Titre abrégé: J Vasc Surg
Pays: United States
ID NLM: 8407742
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
06
06
2019
accepted:
24
08
2019
pubmed:
17
12
2019
medline:
1
12
2020
entrez:
17
12
2019
Statut:
ppublish
Résumé
Interventional approaches to managing intermittent claudication vary widely. According to Society for Vascular Surgery guidelines, any invasive treatment of claudication must offer long-term benefit at low risk of complications. Our aim was to evaluate contemporary claudication intervention patterns and functional outcomes. The Vascular Study Group of New England database (2003-2018) was queried for peripheral vascular interventions (PVIs), infrainguinal bypasses, and suprainguinal bypasses for claudication. Perioperative and 1-year outcomes were evaluated. There were 7051 PVIs, 2527 infrainguinal bypasses, and 849 suprainguinal bypasses performed for claudication. Treatment levels were iliac (52.2%), femoral-popliteal (54%), and tibial (5.7%). Isolated tibial interventions were completed in 1.7% of patients. Infrainguinal bypasses were most often to the popliteal artery (81.2%); however, in 18.8% of cases, bypasses were to tibial targets. Suprainguinal bypasses originated primarily from the abdominal aorta (88.6%) but also from the axillary artery (10.6%) and thoracic aorta (0.8%). Common perioperative complications were access site hematoma in 4.9% of PVIs and cardiac complications in 3.7% of infrainguinal bypasses and 11.3% of suprainguinal bypasses. Overall, 30-day mortality was 0.4% to 2%. After 1 year, of patients initially ambulating without assistance, 2.4% to 3.6% required assistance and 0.3% to 1.3% were nonambulatory. Ipsilateral reintervention/amputation-free survival, major amputation-free survival, and survival at 1 year were 81.4% to 90.6%, 92.9% to 94.1%, and 95.3% to 97%, respectively. Multisegment PVI was the most commonly performed intervention for claudication; however, a subset of patients received treatments supported by limited evidence, including isolated tibial PVI and bypasses with axillary inflow and tibial outflow. Interventions had low perioperative morbidity and mortality, yet patients were still at risk for worse functional status and limb loss at 1 year, emphasizing the importance of careful patient selection, medical optimization, and informed consent.
Identifiants
pubmed: 31839346
pii: S0741-5214(19)32382-1
doi: 10.1016/j.jvs.2019.08.278
pii:
doi:
Types de publication
Journal Article
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
241-249Informations de copyright
Copyright © 2019 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.