Congenital Cytomegalovirus Infection Masquerading as Antenatal Ventriculomegaly With Intraventricular Hemorrhage in a Term Neonate.
cytomegalovirus
hydrocephalous
intraventricular hemorrhage
neonatal cholestasis
Journal
The Neurohospitalist
ISSN: 1941-8744
Titre abrégé: Neurohospitalist
Pays: United States
ID NLM: 101558199
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
entrez:
17
12
2019
pubmed:
17
12
2019
medline:
17
12
2019
Statut:
ppublish
Résumé
Intraventricular hemorrhage is an uncommon manifestation of congenital cytomegalovirus (CMV) infection and has been described in preterm neonates. We discuss a term neonate, who was referred because of intracranial hemorrhage and hydrocephalous detected in the antenatal ultrasound. She had cholestatic jaundice, hepatitis, and thrombocytopenia, with positive polymerase chain reaction for CMV. Neuroimaging revealed reduced sulcation, mildly enlarged ventricles, and multiple periventricular cysts, along with residual hemorrhage in occipital horn of left lateral ventricle. She was started on ganciclovir, following which there was improvement in platelet count, jaundice, as well as transaminase levels.
Identifiants
pubmed: 31839867
doi: 10.1177/1941874419846044
pii: 10.1177_1941874419846044
pmc: PMC6900649
doi:
Types de publication
Case Reports
Langues
eng
Pagination
55-57Informations de copyright
© The Author(s) 2019.
Déclaration de conflit d'intérêts
Declaration of Conflicting Interests: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Références
AJNR Am J Neuroradiol. 1994 Apr;15(4):703-15
pubmed: 8010273
J Neonatal Perinatal Med. 2018;11(2):203-208
pubmed: 29843259
Pathol Int. 2017 Feb;67(2):72-82
pubmed: 28074532
J Perinatol. 2001 Sep;21(6):402-4
pubmed: 11593378
Semin Fetal Neonatal Med. 2007 Jun;12(3):154-9
pubmed: 17337260
Pan Afr Med J. 2015 Nov 13;22:244
pubmed: 26958107
Pediatr Radiol. 2011 Aug;41(8):962-70
pubmed: 21597906
Prenat Diagn. 2003 Oct;23(10):797-800
pubmed: 14558022
J Clin Microbiol. 2013 Jul;51(7):2466-8
pubmed: 23678057
Prenat Diagn. 2002 Jul;22(7):558-61
pubmed: 12124687
Indian J Med Microbiol. 2018 Apr-Jun;36(2):279-281
pubmed: 30084424